Cinalid
Generic Name
Cinaloxacin
Manufacturer
PharmaGen Pharmaceuticals Ltd.
Country
Bangladesh
Loading images...
Price Details
Current market pricing information
| Variant | Unit Price | Strip Price |
|---|---|---|
| cinalid 500 mg tablet | ৳ 40.00 | ৳ 120.00 |
Description
Overview of the medicine
Cinalid 500 mg Tablet is a broad-spectrum fluoroquinolone antibiotic used to treat various bacterial infections.
Uses & Indications
Dosage
Adults
Usually 500 mg once or twice daily, depending on the severity and type of infection. Duration of treatment varies.
Elderly
No specific dose adjustment typically required, but monitor renal function. Max 500 mg once daily for some indications.
Renal_impairment
Dose adjustment required for creatinine clearance < 50 mL/min. Consult a physician.
How to Take
Cinalid tablets should be swallowed whole with a glass of water, with or without food. Do not take with dairy products, antacids, or iron supplements.
Mechanism of Action
Cinaloxacin inhibits bacterial DNA gyrase and topoisomerase IV, enzymes essential for bacterial DNA replication, transcription, repair, and recombination, leading to bacterial cell death.
Pharmacokinetics
Onset
Within 1-2 hours of administration.
Excretion
Primarily excreted unchanged in the urine, with a small portion excreted in feces.
Half life
Approximately 4-6 hours.
Absorption
Rapidly and well absorbed from the gastrointestinal tract; bioavailability is approximately 70-80%.
Metabolism
Minimally metabolized in the liver; main metabolites are active.
Side Effects
Contraindications
- Hypersensitivity to cinaloxacin or other quinolones.
- History of tendinitis or tendon rupture associated with quinolone use.
- Children and adolescents (under 18 years of age) due to potential cartilage damage.
Drug Interactions
Warfarin
May enhance the anticoagulant effect of warfarin, requiring INR monitoring.
Theophylline
May increase theophylline levels and toxicity.
NSAIDs (Non-steroidal anti-inflammatory drugs)
May increase the risk of CNS stimulation and convulsions.
Antacids, Iron, Zinc, Multivitamins with minerals
May reduce cinaloxacin absorption. Take cinaloxacin at least 2 hours before or 6 hours after these products.
Storage
Store below 30°C in a dry place, away from direct light and moisture. Keep out of reach of children.
Overdose
In case of overdose, gastric lavage may be considered. Symptomatic and supportive treatment is recommended. Adequate hydration should be maintained.
Pregnancy & Lactation
Not recommended during pregnancy or lactation unless clearly necessary, as animal studies have shown potential risks. Consult your doctor.
Side Effects
Contraindications
- Hypersensitivity to cinaloxacin or other quinolones.
- History of tendinitis or tendon rupture associated with quinolone use.
- Children and adolescents (under 18 years of age) due to potential cartilage damage.
Drug Interactions
Warfarin
May enhance the anticoagulant effect of warfarin, requiring INR monitoring.
Theophylline
May increase theophylline levels and toxicity.
NSAIDs (Non-steroidal anti-inflammatory drugs)
May increase the risk of CNS stimulation and convulsions.
Antacids, Iron, Zinc, Multivitamins with minerals
May reduce cinaloxacin absorption. Take cinaloxacin at least 2 hours before or 6 hours after these products.
Storage
Store below 30°C in a dry place, away from direct light and moisture. Keep out of reach of children.
Overdose
In case of overdose, gastric lavage may be considered. Symptomatic and supportive treatment is recommended. Adequate hydration should be maintained.
Pregnancy & Lactation
Not recommended during pregnancy or lactation unless clearly necessary, as animal studies have shown potential risks. Consult your doctor.
Frequently Asked Questions
Common questions about this medicine
Pack Sizes
Shelf Life
36 months from the date of manufacture.
Availability
Available in pharmacies and hospitals nationwide
Approval Status
Approved by DGDA
Patent Status
Patent expired
WHO Essential Medicine
YesClinical Trials
Cinaloxacin has undergone extensive clinical trials demonstrating its efficacy and safety in various bacterial infections.
Lab Monitoring
- Renal function tests (e.g., creatinine clearance) in patients with impaired renal function.
- Liver function tests if prolonged treatment or liver impairment is suspected.
Doctor Notes
- Counsel patients on the importance of completing the full course to prevent resistance.
- Advise patients to report any signs of tendon pain, swelling, or rupture immediately.
- Caution about potential CNS effects and photosensitivity.
Patient Guidelines
- Complete the full course of Cinalid as prescribed, even if you feel better.
- Drink plenty of fluids while taking this medication.
- Avoid direct sunlight and use sunscreen as Cinalid can increase sun sensitivity.
Missed Dose Advice
If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and resume your regular dosing schedule. Do not double the dose.
Driving Precautions
Cinalid may cause dizziness or lightheadedness. Avoid driving or operating heavy machinery until you know how the medicine affects you.
Lifestyle Advice
- Maintain good hydration.
- Avoid excessive exposure to sunlight.
Alternative Medicines in Bangladesh
Similar medicines available in the market
Global Brand Names
International brand names for this medicine. Click a brand to search for detailed information.
Other Medicines in Cinalid Brand
Other medicines available under the same brand name
