Ciprox
Generic Name
Ciprofloxacin
Manufacturer
Square Pharmaceuticals Ltd.
Country
Bangladesh
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Price Details
Current market pricing information
| Variant | Unit Price | Strip Price |
|---|---|---|
| ciprox 03 eye drop | ৳ 40.15 | N/A |
| ciprox 250 mg tablet | ৳ 8.53 | ৳ 85.30 |
| ciprox 500 mg tablet | ৳ 15.05 | ৳ 150.50 |
| ciprox 750 mg tablet | ৳ 18.07 | ৳ 108.42 |
| ciprox 03 eye ointment | ৳ 35.00 | N/A |
| ciprox 200 mg injection | ৳ 100.00 | N/A |
Description
Overview of the medicine
Ciprofloxacin is a broad-spectrum antibiotic used to treat various bacterial infections.
Uses & Indications
Dosage
Adults
250-750 mg orally every 12 hours, depending on infection severity and type.
Elderly
Dose adjustment may be needed based on renal function.
Renal_impairment
Reduced dose recommended for creatinine clearance < 50 mL/min.
How to Take
Take with or without food. Do not take with dairy products or antacids containing magnesium/aluminum. Ensure adequate hydration.
Mechanism of Action
Ciprofloxacin inhibits bacterial DNA gyrase and topoisomerase IV, essential enzymes for bacterial DNA replication, transcription, repair, and recombination, leading to bacterial cell death.
Pharmacokinetics
Onset
Within 1 hour for most infections
Excretion
Primarily renal (50-70% as unchanged drug), some fecal excretion.
Half life
3-5 hours
Absorption
Rapid and well absorbed orally, bioavailability 70-80%. Peak plasma concentrations achieved within 1-2 hours.
Metabolism
Partially metabolized in the liver (15-30%) to less active metabolites.
Side Effects
Contraindications
- Hypersensitivity to ciprofloxacin or other fluoroquinolones.
- Concomitant use with tizanidine.
Drug Interactions
NSAIDs
May increase risk of CNS stimulation and convulsive seizures.
Warfarin
Increased anticoagulant effect.
Tizanidine
Increased tizanidine levels, leading to hypotension and somnolence.
Theophylline
Increased theophylline levels, risk of toxicity.
Antacids (Mg/Al)
Reduced absorption of ciprofloxacin.
Storage
Store below 30°C, protected from light and moisture.
Overdose
Gastric lavage, symptomatic and supportive care. Hemodialysis or peritoneal dialysis is not effective.
Pregnancy & Lactation
Pregnancy Category C. Use only if potential benefit justifies potential risk to the fetus. Excreted in breast milk, avoid during lactation or discontinue breastfeeding.
Frequently Asked Questions
Common questions about this medicine
Pack Sizes
Shelf Life
24-36 months
Availability
Pharmacies, Hospitals
Approval Status
FDA and DGDA approved
Patent Status
Generic available
WHO Essential Medicine
YesClinical Trials
Ciprofloxacin has been extensively studied for various bacterial infections; ongoing research for new applications.
Lab Monitoring
- Renal function tests
- Liver function tests (if prolonged therapy)
- Complete blood count
Doctor Notes
- Counsel patients thoroughly on Black Box warnings, especially regarding tendon issues and neurological adverse events.
- Avoid in patients with myasthenia gravis or a history of QT prolongation.
Patient Guidelines
- Complete the full course of medication even if symptoms improve.
- Stay well-hydrated during treatment.
- Avoid excessive sun exposure due to photosensitivity.
Missed Dose Advice
Take the missed dose as soon as you remember, unless it is almost time for your next dose. Do not double the dose.
Driving Precautions
May cause dizziness or lightheadedness, which can impair ability to drive or operate machinery. Exercise caution.
Lifestyle Advice
- Avoid strenuous exercise if experiencing tendon pain. Limit caffeine intake as ciprofloxacin can increase caffeine effects.
Alternative Medicines in Bangladesh
Similar medicines available in the market
Global Brand Names
International brand names for this medicine. Click a brand to search for detailed information.