Cipzin
Generic Name
Ciprofloxacin
Manufacturer
Square Pharmaceuticals Ltd.
Country
Bangladesh
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Price Details
Current market pricing information
| Variant | Unit Price | Strip Price |
|---|---|---|
| cipzin 5 mg syrup | ৳ 20.00 | N/A |
| cipzin 10 mg tablet | ৳ 2.00 | N/A |
Description
Overview of the medicine
Cipzin is a fluoroquinolone antibiotic used to treat a variety of bacterial infections.
Uses & Indications
Dosage
Adults
250-750 mg orally twice daily, depending on infection type and severity.
Elderly
Similar to adults, but consider renal function.
Renal_impairment
Dose adjustment required based on creatinine clearance.
How to Take
Can be taken with or without food. Avoid taking with dairy products or antacids.
Mechanism of Action
Ciprofloxacin inhibits bacterial DNA gyrase and topoisomerase IV, enzymes necessary for bacterial DNA replication, transcription, repair, and recombination.
Pharmacokinetics
Onset
1-2 hours
Excretion
Primarily excreted renally (50-70% unchanged drug), some fecal excretion.
Half life
3-5 hours
Absorption
Rapidly and well absorbed after oral administration. Bioavailability of 70-80%.
Metabolism
Partially metabolized in the liver (CYP1A2).
Side Effects
Contraindications
- Hypersensitivity to ciprofloxacin or other fluoroquinolones
- Concomitant administration with tizanidine
Drug Interactions
Warfarin
Increased anticoagulant effect.
Tizanidine
Concomitant use is contraindicated due to increased tizanidine levels.
Theophylline
Increased theophylline levels and toxicity.
Antacids/Dairy Products
Reduced absorption of ciprofloxacin.
Storage
Store in a cool, dry place, away from light and moisture. Keep out of reach of children.
Overdose
Gastric lavage, activated charcoal, supportive care, and adequate hydration.
Pregnancy & Lactation
Use only if potential benefit justifies the potential risk to the fetus/infant. Consult doctor.
Side Effects
Contraindications
- Hypersensitivity to ciprofloxacin or other fluoroquinolones
- Concomitant administration with tizanidine
Drug Interactions
Warfarin
Increased anticoagulant effect.
Tizanidine
Concomitant use is contraindicated due to increased tizanidine levels.
Theophylline
Increased theophylline levels and toxicity.
Antacids/Dairy Products
Reduced absorption of ciprofloxacin.
Storage
Store in a cool, dry place, away from light and moisture. Keep out of reach of children.
Overdose
Gastric lavage, activated charcoal, supportive care, and adequate hydration.
Pregnancy & Lactation
Use only if potential benefit justifies the potential risk to the fetus/infant. Consult doctor.
Frequently Asked Questions
Common questions about this medicine
Pack Sizes
Shelf Life
36 months
Availability
Available in all pharmacies nationwide
Approval Status
Approved by DGDA (Bangladesh)
Patent Status
Patent expired
WHO Essential Medicine
YesClinical Trials
Numerous clinical trials have established ciprofloxacin's efficacy and safety for various bacterial infections.
Lab Monitoring
- Renal function tests (for prolonged therapy or renal impairment)
- Liver function tests
- Blood counts (rarely)
Doctor Notes
- Counsel patients on potential tendon adverse effects.
- Avoid in patients with myasthenia gravis.
- Monitor for QT prolongation, especially with concomitant medications.
Patient Guidelines
- Complete the full course of treatment even if symptoms improve.
- Stay hydrated.
- Avoid excessive sunlight exposure.
- Report any joint pain or unusual tingling/numbness immediately.
Missed Dose Advice
Take the missed dose as soon as you remember. If it is almost time for your next dose, skip the missed dose and resume your regular dosing schedule. Do not double the dose.
Driving Precautions
May cause dizziness or lightheadedness; caution advised when driving or operating machinery.
Lifestyle Advice
- Maintain good hygiene to prevent reinfections.
- Eat a balanced diet.
Alternative Medicines in Bangladesh
Similar medicines available in the market
Global Brand Names
International brand names for this medicine. Click a brand to search for detailed information.
Other Medicines in Cipzin Brand
Other medicines available under the same brand name
