Civodex
Generic Name
Cefodoxime Proxetil
Manufacturer
PharmaLife Bangladesh Ltd.
Country
Bangladesh
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Price Details
Current market pricing information
| Variant | Unit Price | Strip Price |
|---|---|---|
| civodex 03 01 eye drop | ৳ 75.28 | N/A |
Description
Overview of the medicine
Civodex (Cefodoxime Proxetil) is a broad-spectrum oral cephalosporin antibiotic used to treat various bacterial infections.
Uses & Indications
Dosage
Adults
200 mg every 12 hours for 7-14 days, depending on infection type.
Elderly
No dose adjustment typically required unless severe renal impairment.
Renal_impairment
Dose reduction or increased dosing interval may be necessary based on creatinine clearance.
How to Take
Take orally, preferably with food, to enhance absorption.
Mechanism of Action
Cefodoxime Proxetil acts by inhibiting bacterial cell wall synthesis, leading to bacterial cell lysis and death.
Pharmacokinetics
Onset
1-2 hours
Excretion
Primarily excreted unchanged in the urine.
Half life
2-3 hours
Absorption
Rapidly absorbed from the gastrointestinal tract and hydrolyzed to Cefodoxime.
Metabolism
Mainly hydrolyzed to Cefodoxime; minimal hepatic metabolism.
Side Effects
Contraindications
- Known hypersensitivity to Cefodoxime, other cephalosporins, or any component of the formulation.
- History of severe hypersensitivity reaction to any penicillin.
Drug Interactions
Probenecid
May increase Cefodoxime plasma levels by decreasing renal excretion.
Antacids/H2 blockers
May decrease absorption of Cefodoxime. Administer Cefodoxime 2-3 hours before or after these agents.
Storage
Store below 30°C in a dry place, away from light and moisture.
Overdose
In case of overdose, seek immediate medical attention. Management is supportive and symptomatic, possibly including gastric lavage.
Pregnancy & Lactation
Use during pregnancy only if clearly needed. Excreted in breast milk; caution advised during lactation.
Side Effects
Contraindications
- Known hypersensitivity to Cefodoxime, other cephalosporins, or any component of the formulation.
- History of severe hypersensitivity reaction to any penicillin.
Drug Interactions
Probenecid
May increase Cefodoxime plasma levels by decreasing renal excretion.
Antacids/H2 blockers
May decrease absorption of Cefodoxime. Administer Cefodoxime 2-3 hours before or after these agents.
Storage
Store below 30°C in a dry place, away from light and moisture.
Overdose
In case of overdose, seek immediate medical attention. Management is supportive and symptomatic, possibly including gastric lavage.
Pregnancy & Lactation
Use during pregnancy only if clearly needed. Excreted in breast milk; caution advised during lactation.
Frequently Asked Questions
Common questions about this medicine
Pack Sizes
Shelf Life
24 months from manufacturing date
Availability
Pharmacies nationwide
Approval Status
Approved by DGDA
Patent Status
Generic available
WHO Essential Medicine
YesClinical Trials
Extensive clinical trials have demonstrated the efficacy and safety of Cefodoxime Proxetil in various bacterial infections.
Lab Monitoring
- Renal function tests (for prolonged therapy or in patients with renal impairment)
- Complete blood count (rarely)
Doctor Notes
- Advise patients to complete the entire course of therapy to prevent recurrence and resistance.
- Monitor for signs of C. difficile infection if diarrhea develops during or after treatment.
Patient Guidelines
- Complete the full course of medication, even if symptoms improve.
- Do not share this medication with others.
- Contact your doctor if symptoms do not improve or worsen.
Missed Dose Advice
If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue your regular dosing schedule. Do not double the dose.
Driving Precautions
Generally, Civodex does not impair the ability to drive or operate machinery. However, if side effects like dizziness occur, avoid such activities.
Lifestyle Advice
- Maintain good hydration.
- Avoid alcohol during treatment as it may exacerbate side effects.
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Global Brand Names
International brand names for this medicine. Click a brand to search for detailed information.
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