Clasrin
Generic Name
Hydrocortisone 1% w/w cream
Manufacturer
Fictional Pharma Ltd.
Country
Bangladesh
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Price Details
Current market pricing information
| Variant | Unit Price | Strip Price |
|---|---|---|
| clasrin 1 w cream | ৳ 840.00 | N/A |
Description
Overview of the medicine
Clasrin 1% w/w cream contains Hydrocortisone, a mild corticosteroid used to reduce inflammation, redness, and itching associated with various skin conditions.
Uses & Indications
Dosage
Adults
Apply a thin film to the affected skin area 1-2 times daily. Do not use for more than 7 days without medical advice.
Elderly
No specific dosage adjustment required; use with caution due to thinner skin.
Renal_impairment
No specific dosage adjustment required for topical use.
How to Take
For external use only. Apply a thin, even layer of cream to the clean, dry affected skin area. Gently rub it in until it disappears. Wash hands before and after application.
Mechanism of Action
Hydrocortisone works by inhibiting the release of substances in the body that cause inflammation. It suppresses the immune response, thereby reducing swelling, itching, and redness in the affected skin area.
Pharmacokinetics
Onset
Within hours of application.
Excretion
Excreted mainly in the urine as metabolites.
Half life
Approximately 8-12 hours in skin, faster systemically.
Absorption
Minimal systemic absorption through intact skin. Increased absorption with occlusive dressings, inflamed skin, or prolonged use.
Metabolism
Primarily metabolized in the skin, liver, and kidneys.
Side Effects
Contraindications
- Hypersensitivity to hydrocortisone or any component of the cream
- Untreated bacterial, fungal, or viral infections (e.g., herpes simplex, chickenpox)
- Perioral dermatitis
- Rosacea
- Acne vulgaris
- Perianal and genital pruritus
Drug Interactions
Systemic Corticosteroids
Increased risk of systemic effects if used extensively or for prolonged periods with other corticosteroids.
Storage
Store below 25°C, away from direct sunlight and moisture. Do not freeze. Keep out of reach of children.
Overdose
Acute overdose is unlikely with topical use. Prolonged or extensive use may lead to systemic effects like Cushing's syndrome, adrenal suppression, or skin atrophy. Management involves gradual withdrawal of the drug and symptomatic treatment.
Pregnancy & Lactation
Limited topical use may be considered during pregnancy and lactation if clearly necessary, after consulting a doctor. Avoid large areas or prolonged use.
Side Effects
Contraindications
- Hypersensitivity to hydrocortisone or any component of the cream
- Untreated bacterial, fungal, or viral infections (e.g., herpes simplex, chickenpox)
- Perioral dermatitis
- Rosacea
- Acne vulgaris
- Perianal and genital pruritus
Drug Interactions
Systemic Corticosteroids
Increased risk of systemic effects if used extensively or for prolonged periods with other corticosteroids.
Storage
Store below 25°C, away from direct sunlight and moisture. Do not freeze. Keep out of reach of children.
Overdose
Acute overdose is unlikely with topical use. Prolonged or extensive use may lead to systemic effects like Cushing's syndrome, adrenal suppression, or skin atrophy. Management involves gradual withdrawal of the drug and symptomatic treatment.
Pregnancy & Lactation
Limited topical use may be considered during pregnancy and lactation if clearly necessary, after consulting a doctor. Avoid large areas or prolonged use.
Frequently Asked Questions
Common questions about this medicine
Pack Sizes
Shelf Life
Typically 24-36 months from manufacturing date.
Availability
Pharmacies, Hospitals
Approval Status
Approved (for Hydrocortisone)
Patent Status
Generic available
WHO Essential Medicine
YesClinical Trials
Numerous clinical trials have established the efficacy and safety of hydrocortisone for various dermatological conditions.
Lab Monitoring
- Not routinely required for topical use, unless concerns about systemic absorption with extensive or prolonged use (e.g., adrenal function tests).
Doctor Notes
- Counsel patients on appropriate application technique and duration of use.
- Advise against using on infected skin without concomitant antimicrobial therapy.
- Monitor for signs of skin atrophy or other local side effects.
- Consider alternative non-steroidal options for mild cases or maintenance therapy.
Patient Guidelines
- Apply sparingly and only to the affected area.
- Avoid contact with eyes, mouth, and other mucous membranes.
- Do not cover the treated area with bandages or occlusive dressings unless advised by a doctor.
- Wash hands thoroughly after application.
- Do not use for more than the recommended duration.
Missed Dose Advice
If you miss a dose, apply it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not apply a double dose to make up for a missed one.
Driving Precautions
Clasrin 1% w/w cream is for topical use and is unlikely to affect the ability to drive or operate machinery.
Lifestyle Advice
- Keep affected skin clean and moisturized.
- Avoid known irritants or allergens.
- Wear loose, breathable clothing to minimize irritation.
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Global Brand Names
International brand names for this medicine. Click a brand to search for detailed information.