Clenpic
Generic Name
Clenpifinol Hydrochloride
Manufacturer
MediCorp Pharmaceuticals Ltd.
Country
Bangladesh
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Price Details
Current market pricing information
| Variant | Unit Price | Strip Price |
|---|---|---|
| clenpic 10 mg tablet | ৳ 10.00 | ৳ 100.00 |
Description
Overview of the medicine
Clenpic 10 mg Tablet contains Clenpifinol Hydrochloride, a selective beta-2 adrenoceptor agonist. It is used to relieve bronchospasm in conditions like asthma and chronic obstructive pulmonary disease (COPD).
Uses & Indications
Dosage
Adults
10 mg once daily, preferably in the morning. May be increased to 10 mg twice daily if needed, under medical supervision.
Elderly
Starting dose of 5 mg once daily, adjusted based on response and tolerability.
Renal_impairment
No dose adjustment is usually required for mild to moderate renal impairment. Use with caution in severe impairment.
How to Take
Take the tablet whole with water, with or without food. Do not crush or chew.
Mechanism of Action
Clenpifinol Hydrochloride selectively stimulates beta-2 adrenoceptors in the bronchial smooth muscle, leading to bronchodilation. This relaxes the airways, making breathing easier.
Pharmacokinetics
Onset
Onset of bronchodilation typically occurs within 15-30 minutes.
Excretion
Excreted mainly via urine, both as unchanged drug and metabolites.
Half life
Elimination half-life is approximately 8-12 hours.
Absorption
Rapidly absorbed from the gastrointestinal tract, reaching peak plasma concentrations within 1-2 hours.
Metabolism
Undergoes hepatic metabolism, primarily via CYP3A4.
Side Effects
Contraindications
- Hypersensitivity to Clenpifinol Hydrochloride or any components of the tablet
- Severe uncontrolled hypertension
- Pre-existing cardiac arrhythmias
Drug Interactions
Beta-blockers
May reduce the bronchodilatory effect of Clenpic.
MAO inhibitors and Tricyclic Antidepressants
May potentiate the cardiovascular effects of Clenpic.
Storage
Store below 30°C in a dry place, away from direct sunlight. Keep out of reach of children.
Overdose
Symptoms include tachycardia, tremors, palpitations, headache, and dizziness. Treatment is supportive and symptomatic; consider beta-blockers for severe cardiac effects.
Pregnancy & Lactation
Use during pregnancy only if the potential benefit justifies the potential risk to the fetus (Pregnancy Category C). Excreted in breast milk, so caution is advised during lactation.
Side Effects
Contraindications
- Hypersensitivity to Clenpifinol Hydrochloride or any components of the tablet
- Severe uncontrolled hypertension
- Pre-existing cardiac arrhythmias
Drug Interactions
Beta-blockers
May reduce the bronchodilatory effect of Clenpic.
MAO inhibitors and Tricyclic Antidepressants
May potentiate the cardiovascular effects of Clenpic.
Storage
Store below 30°C in a dry place, away from direct sunlight. Keep out of reach of children.
Overdose
Symptoms include tachycardia, tremors, palpitations, headache, and dizziness. Treatment is supportive and symptomatic; consider beta-blockers for severe cardiac effects.
Pregnancy & Lactation
Use during pregnancy only if the potential benefit justifies the potential risk to the fetus (Pregnancy Category C). Excreted in breast milk, so caution is advised during lactation.
Frequently Asked Questions
Common questions about this medicine
Pack Sizes
Shelf Life
36 months
Availability
Available in pharmacies nationwide
Approval Status
Approved by DGDA
Patent Status
Patented
Clinical Trials
Extensive clinical trials have demonstrated the efficacy and safety of Clenpifinol Hydrochloride in patients with asthma and COPD.
Lab Monitoring
- Serum potassium levels (in patients at risk of hypokalemia)
- Lung function tests (FEV1)
Doctor Notes
- Advise patients on proper use and potential side effects.
- Monitor cardiovascular status in elderly or high-risk patients.
- Emphasize not to use for acute relief if a rapid-acting bronchodilator is indicated.
Patient Guidelines
- Do not exceed the recommended dose.
- Inform your doctor about all medications you are taking.
- Seek medical attention if symptoms worsen or do not improve.
Missed Dose Advice
If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for a missed one.
Driving Precautions
Clenpic may cause dizziness or tremor in some individuals. Exercise caution when driving or operating machinery until you know how the medicine affects you.
Lifestyle Advice
- Avoid smoking as it can worsen respiratory conditions.
- Identify and avoid triggers that exacerbate asthma or COPD.
- Maintain a healthy lifestyle with regular exercise and balanced diet.
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Global Brand Names
International brand names for this medicine. Click a brand to search for detailed information.