Clopirox
Generic Name
Ciclopirox Olamine 1% Shampoo
Manufacturer
Various Generic Manufacturers
Country
Global
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Price Details
Current market pricing information
| Variant | Unit Price | Strip Price |
|---|---|---|
| clopirox 1 shampoo | ৳ 350.00 | N/A |
Description
Overview of the medicine
Clopirox 1% Shampoo is an antifungal medication used to treat seborrheic dermatitis of the scalp, a common condition causing red, flaky, itchy skin.
Uses & Indications
Dosage
Adults
Wet hair and scalp, apply approximately 5 mL (1 teaspoon) of shampoo, lather well, and leave on scalp for 3-5 minutes. Rinse thoroughly. Use twice weekly for 4 weeks, with at least 3 days between applications. Do not use more than twice a week.
Elderly
No specific dosage adjustments required for elderly patients.
Renal_impairment
No dosage adjustment needed as systemic absorption is minimal.
How to Take
For external use only. Apply to wet hair and scalp, lather, leave for 3-5 minutes, then rinse thoroughly. Avoid contact with eyes.
Mechanism of Action
Ciclopirox olamine inhibits the growth of various fungi, yeasts, and dermatophytes by chelating polyvalent metal ions, which leads to the inhibition of essential fungal enzyme systems, disrupting cell membrane integrity, and interfering with nucleic acid and protein synthesis.
Pharmacokinetics
Onset
Symptom improvement (e.g., scaling, itching) typically begins within 1-2 weeks of consistent use, with full effect achieved over 4 weeks.
Excretion
Systemically absorbed metabolites are excreted predominantly via the kidneys.
Half life
Not clinically relevant for topical administration due to minimal systemic absorption.
Absorption
Very low systemic absorption (typically <1%) from topical application to the scalp. Most of the drug remains on the skin surface.
Metabolism
Any systemically absorbed Ciclopirox Olamine is extensively metabolized, primarily by glucuronidation.
Side Effects
Contraindications
- Known hypersensitivity to ciclopirox olamine or any component of the shampoo.
Drug Interactions
Topical corticosteroids
No significant interactions reported, but caution is advised with prolonged co-administration as corticosteroids may suppress local immune response.
Storage
Store below 25°C (77°F). Protect from light and moisture. Do not freeze. Keep the bottle tightly closed.
Overdose
Overdose is unlikely with topical application. If accidentally ingested, seek medical advice or contact a poison control center immediately.
Pregnancy & Lactation
Use in pregnancy and lactation should only be considered if the potential benefit outweighs the potential risk. Consult a doctor. Systemic absorption is minimal.
Frequently Asked Questions
Common questions about this medicine
Pack Sizes
Shelf Life
24 to 36 months when stored properly.
Availability
Pharmacies, drugstores
Approval Status
Approved
Patent Status
Off-patent
Clinical Trials
Multiple clinical trials have demonstrated the efficacy and safety of ciclopirox 1% shampoo in the treatment of seborrheic dermatitis, showing significant reduction in scaling, itching, and erythema compared to placebo.
Lab Monitoring
- No specific lab monitoring is required for topical clopirox shampoo.
Doctor Notes
- Advise patients on the correct application technique and duration of treatment to ensure optimal efficacy and minimize side effects.
- Counsel patients that symptoms may worsen initially before improvement is observed.
- Emphasize avoiding contact with eyes and not ingesting the shampoo.
Patient Guidelines
- Use exactly as directed by your doctor or as instructed on the label.
- Avoid contact with eyes; if contact occurs, rinse thoroughly with water.
- Do not swallow. Keep out of reach of children.
- Complete the full course of treatment, even if symptoms improve.
- Do not apply to open wounds or irritated skin without medical advice.
Missed Dose Advice
If a dose is missed, apply it as soon as remembered. Then continue with the regular schedule. Do not double the dose to catch up.
Driving Precautions
Clopirox 1% Shampoo is for external topical use only and is not expected to affect the ability to drive or operate machinery.
Lifestyle Advice
- Maintain good scalp hygiene.
- Avoid sharing combs, brushes, hats, or other personal items to prevent spreading fungal infections.
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Global Brand Names
International brand names for this medicine. Click a brand to search for detailed information.