Codliv Forte
Generic Name
Codliv
Manufacturer
Various manufacturers (e.g., Seven Seas, Square)
Country
Global, e.g., UK, Bangladesh
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Description
Overview of the medicine
Cod liver oil is a dietary supplement derived from the liver of cod fish. It is rich in omega-3 fatty acids (EPA and DHA), Vitamin A, and Vitamin D. It is commonly used for its nutritional benefits, including supporting bone health, vision, and cardiovascular function.
Uses & Indications
Dosage
Adults
1-2 capsules or 5-10 ml liquid daily, or as directed by a physician.
Elderly
Same as adult dosage, or as directed by a physician.
Renal_impairment
No specific dose adjustment generally required, but consult a physician, especially with severe impairment due to potential Vitamin D accumulation.
How to Take
Take orally, preferably with a meal to enhance absorption and reduce gastrointestinal upset.
Mechanism of Action
Provides essential fatty acids (omega-3s) which have anti-inflammatory properties and support cellular function. Vitamin A is crucial for vision, immune function, and cell growth. Vitamin D is essential for calcium absorption, bone health, and immune system regulation.
Pharmacokinetics
Onset
Nutritional benefits are gradual and cumulative.
Excretion
Metabolites of fatty acids, Vitamin A, and Vitamin D are excreted via bile and kidneys.
Half life
Variable, depending on specific components and body stores (e.g., Vitamin D half-life can be weeks).
Absorption
Well absorbed from the gastrointestinal tract, especially when taken with food due to its fat-soluble nature.
Metabolism
Fatty acids are metabolized via beta-oxidation. Vitamins A and D are metabolized in the liver.
Side Effects
Contraindications
- Hypersensitivity to cod liver oil or any of its components
- Hypervitaminosis A or D
- Bleeding disorders (use with caution due to omega-3's mild anti-coagulant effect)
- Severe liver disease
Drug Interactions
Orlistat
May reduce absorption of fat-soluble vitamins (A and D).
Anticoagulants (e.g., Warfarin)
May increase the risk of bleeding due to omega-3 fatty acids.
High doses of Vitamin A or D supplements
Risk of hypervitaminosis A or D.
Storage
Store in a cool, dry place, below 25°C, away from direct sunlight and moisture. Refrigerate liquid forms after opening.
Overdose
Symptoms of overdose include nausea, vomiting, diarrhea, hypercalcemia (from excess Vitamin D), and symptoms of hypervitaminosis A (e.g., dry skin, fatigue, headache, bone pain). Treatment is supportive and symptomatic, discontinuing the supplement.
Pregnancy & Lactation
Generally considered safe at recommended doses, but always consult a physician before use. Excessive Vitamin A can be teratogenic.
Side Effects
Contraindications
- Hypersensitivity to cod liver oil or any of its components
- Hypervitaminosis A or D
- Bleeding disorders (use with caution due to omega-3's mild anti-coagulant effect)
- Severe liver disease
Drug Interactions
Orlistat
May reduce absorption of fat-soluble vitamins (A and D).
Anticoagulants (e.g., Warfarin)
May increase the risk of bleeding due to omega-3 fatty acids.
High doses of Vitamin A or D supplements
Risk of hypervitaminosis A or D.
Storage
Store in a cool, dry place, below 25°C, away from direct sunlight and moisture. Refrigerate liquid forms after opening.
Overdose
Symptoms of overdose include nausea, vomiting, diarrhea, hypercalcemia (from excess Vitamin D), and symptoms of hypervitaminosis A (e.g., dry skin, fatigue, headache, bone pain). Treatment is supportive and symptomatic, discontinuing the supplement.
Pregnancy & Lactation
Generally considered safe at recommended doses, but always consult a physician before use. Excessive Vitamin A can be teratogenic.
Frequently Asked Questions
Common questions about this medicine
Pack Sizes
Shelf Life
Typically 2-3 years from manufacturing date, check packaging for specific expiry.
Availability
Pharmacies, supermarkets, online stores
Approval Status
Over-the-counter (OTC) supplement
Patent Status
Expired/Not applicable (generic)
Clinical Trials
Extensive research exists on omega-3 fatty acids, Vitamin A, and Vitamin D. Specific trials for generic cod liver oil focus on its role in cardiovascular health, inflammatory conditions, and nutritional supplementation.
Lab Monitoring
- Plasma Vitamin D levels (25-hydroxyvitamin D) if deficiency is suspected or high doses are used.
- Liver function tests with long-term high dose use.
- Calcium levels (due to Vitamin D).
Doctor Notes
- Advise patients on the importance of adhering to recommended dosages to avoid hypervitaminosis.
- Highlight its role as a supplement, not a replacement for a balanced diet.
- Caution against use with anticoagulants without medical supervision.
Patient Guidelines
- Take as directed by a healthcare professional.
- Do not exceed the recommended dose.
- Store in a cool, dry place away from direct sunlight.
- Keep out of reach of children.
Missed Dose Advice
If a dose is missed, take it as soon as remembered. If it is close to the time for the next dose, skip the missed dose and resume the regular dosing schedule. Do not double the dose.
Driving Precautions
Cod liver oil does not typically impair the ability to drive or operate machinery.
Lifestyle Advice
- Maintain a balanced diet rich in fruits, vegetables, and whole grains.
- Engage in regular physical activity.
- Avoid smoking and excessive alcohol.
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Global Brand Names
International brand names for this medicine. Click a brand to search for detailed information.