Conlax
Generic Name
Polyethylene Glycol 3350
Manufacturer
Hypothetical Pharma Co.
Country
Bangladesh
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Price Details
Current market pricing information
| Variant | Unit Price | Strip Price |
|---|---|---|
| conlax 335 gm oral solution | ৳ 140.00 | N/A |
Description
Overview of the medicine
Conlax 335 gm Oral Solution contains Polyethylene Glycol 3350, an osmotic laxative. It is primarily used for complete bowel cleansing before medical procedures (such as colonoscopy) or for severe fecal impaction, where high doses of laxatives are required to soften and evacuate stool.
Uses & Indications
Dosage
Adults
For bowel preparation: Dissolve the entire 335 gm contents of one sachet/container in 2 to 3 liters of water. Drink the solution over a period of 2 to 4 hours, as directed by a healthcare professional. For fecal impaction: Dosage varies, often involving higher doses over several days; consult a doctor.
Elderly
Similar dosage as adults, but monitor for electrolyte disturbances and hydration status, especially in frail patients. Close medical supervision is recommended.
Renal_impairment
Use with caution and under medical supervision. Dosage adjustment may be required based on clinical assessment.
How to Take
Empty the entire contents of the sachet/container into a suitable container. Add the recommended amount of water (typically 2-3 liters) and stir until the powder is completely dissolved. Drink the solution gradually over the prescribed time period.
Mechanism of Action
Polyethylene Glycol 3350 (PEG 3350) acts as an osmotic agent, drawing water into the colon. This increases the water content and volume of the stool, softening it and promoting bowel movements.
Pharmacokinetics
Onset
Onset of action is typically within 24 to 48 hours for chronic constipation, but for bowel preparation, effects are usually seen within a few hours of administration.
Excretion
Primarily excreted unchanged in the feces. The small absorbed fraction is excreted in urine.
Half life
Not relevant due to minimal systemic absorption.
Absorption
Minimally absorbed from the gastrointestinal tract (less than 1%).
Metabolism
Not metabolized by intestinal flora or in the liver.
Side Effects
Contraindications
- Known hypersensitivity to Polyethylene Glycol.
- Gastrointestinal obstruction or perforation.
- Toxic megacolon or severe inflammatory bowel disease.
Drug Interactions
Other Oral Medications
May reduce the absorption of other orally administered medications if taken concurrently. It is advisable to take other medications at least 1 hour before or several hours after consuming Conlax.
Storage
Store below 30°C. Protect from moisture and direct sunlight. Keep out of reach of children. Once reconstituted, the solution should be used within 24 hours.
Overdose
Overdose may lead to severe diarrhea, abdominal discomfort, dehydration, and electrolyte disturbances. Management involves supportive care, fluid and electrolyte replacement.
Pregnancy & Lactation
Generally considered safe for use during pregnancy and lactation due to minimal systemic absorption, but it is always advisable to consult a healthcare professional before use.
Side Effects
Contraindications
- Known hypersensitivity to Polyethylene Glycol.
- Gastrointestinal obstruction or perforation.
- Toxic megacolon or severe inflammatory bowel disease.
Drug Interactions
Other Oral Medications
May reduce the absorption of other orally administered medications if taken concurrently. It is advisable to take other medications at least 1 hour before or several hours after consuming Conlax.
Storage
Store below 30°C. Protect from moisture and direct sunlight. Keep out of reach of children. Once reconstituted, the solution should be used within 24 hours.
Overdose
Overdose may lead to severe diarrhea, abdominal discomfort, dehydration, and electrolyte disturbances. Management involves supportive care, fluid and electrolyte replacement.
Pregnancy & Lactation
Generally considered safe for use during pregnancy and lactation due to minimal systemic absorption, but it is always advisable to consult a healthcare professional before use.
Frequently Asked Questions
Common questions about this medicine
Pack Sizes
Shelf Life
Typically 2-3 years when stored as directed.
Availability
Pharmacies, supermarkets
Approval Status
Approved by major regulatory bodies
Patent Status
Generic available
WHO Essential Medicine
YesClinical Trials
Extensive clinical trials have established the efficacy and safety of Polyethylene Glycol 3350 for bowel preparation and chronic constipation. Studies show high success rates in achieving adequate bowel cleansing.
Lab Monitoring
- Electrolyte levels (especially for prolonged or high-dose use, or in patients with impaired renal function)
Doctor Notes
- Ensure patient is adequately hydrated before, during, and after administration.
- Carefully assess patients with known cardiac or renal conditions for electrolyte disturbances.
Patient Guidelines
- Follow preparation and administration instructions carefully.
- Drink adequate fluids throughout the day to prevent dehydration.
- Report any severe abdominal pain, vomiting, or allergic reactions to your doctor.
Missed Dose Advice
This medicine is typically used for single-event bowel preparation, so a missed dose scenario is generally not applicable. For other uses, follow your doctor's instructions.
Driving Precautions
Conlax 335 gm Oral Solution is not expected to affect the ability to drive or operate machinery.
Lifestyle Advice
- Maintain a balanced diet and regular exercise to support healthy bowel function once the acute issue is resolved.
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Global Brand Names
International brand names for this medicine. Click a brand to search for detailed information.