Coralcin-D
Generic Name
Calcium Carbonate + Cholecalciferol
Manufacturer
ACME Laboratories Ltd.
Country
Bangladesh
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Price Details
Current market pricing information
| Variant | Unit Price | Strip Price |
|---|---|---|
| coralcin d 500 mg tablet | ৳ 11.50 | ৳ 115.00 |
Description
Overview of the medicine
Coralcin-D is a combined supplement of Calcium and Vitamin D3, used to prevent and treat calcium and vitamin D deficiencies, and to maintain healthy bones.
Uses & Indications
Dosage
Adults
Typically 1-2 tablets daily, or as directed by the physician. Should be taken with food for better absorption.
Elderly
Same as adults, but monitor calcium levels closely, especially in those with renal impairment.
Renal_impairment
Use with caution. Dosage adjustment may be required. Contraindicated in severe renal impairment.
How to Take
Oral. Tablets can be chewed or swallowed whole with water, preferably with meals.
Mechanism of Action
Calcium is an essential mineral required for bone formation, muscle contraction, and nerve function. Vitamin D3 (cholecalciferol) helps regulate calcium and phosphate metabolism, facilitating their absorption from the gut and deposition into bone tissue.
Pharmacokinetics
Onset
Clinical effects are gradual, not immediate.
Excretion
Calcium is excreted primarily via kidneys and feces. Vitamin D3 metabolites are primarily excreted in bile and feces, with some renal excretion.
Half life
Calcium: Varies. Vitamin D3: Parent compound ~24 hours, active metabolite calcitriol ~3-5 days.
Absorption
Calcium absorption is mainly in the small intestine, about 20-30% of ingested dose. Vitamin D3 is absorbed in the small intestine, primarily in the jejunum and ileum, then metabolized in the liver and kidney.
Metabolism
Calcium is not metabolized in the classic sense. Vitamin D3 is hydroxylated in the liver to 25-hydroxyvitamin D3, and then in the kidneys to the active form, 1,25-dihydroxyvitamin D3 (calcitriol).
Side Effects
Contraindications
- Hypercalcemia
- Hypercalciuria
- Severe renal impairment
- Known hypersensitivity to calcium, vitamin D, or any excipients
Drug Interactions
Iron supplements
Calcium may reduce iron absorption; take separately.
Cardiac glycosides
May increase the risk of cardiac arrhythmias.
Thiazide diuretics
May increase the risk of hypercalcemia.
Bisphosphonates and Levothyroxine
Absorption may be reduced; take at least 30-60 minutes apart.
Tetracyclines and Fluoroquinolones
Calcium can reduce their absorption; take at least 2-3 hours apart.
Storage
Store in a cool, dry place, below 30°C. Protect from light and moisture. Keep out of reach of children.
Overdose
Symptoms: Nausea, vomiting, constipation, thirst, polyuria, anorexia, weakness, fatigue. Management: Discontinue medication, hydrate, and monitor serum calcium levels. Severe cases may require hospitalization and specific treatments.
Pregnancy & Lactation
Safe for use during pregnancy and lactation, but calcium and vitamin D intake should be monitored to avoid hypercalcemia in the mother or fetus/infant.
Frequently Asked Questions
Common questions about this medicine
Pack Sizes
Shelf Life
Typically 24-36 months from manufacturing date.
Availability
Available in all pharmacies and hospitals
Approval Status
Approved by DGDA
Patent Status
Generic drug
WHO Essential Medicine
YesClinical Trials
Well-established and widely studied combination; numerous clinical trials support efficacy in bone health and deficiency states.
Lab Monitoring
- Serum calcium levels (especially with long-term use or renal impairment)
- Serum phosphate levels
- Urinary calcium excretion (if hypercalciuria suspected)
Doctor Notes
- Advise patients on appropriate diet and lifestyle changes.
- Regular monitoring of serum calcium levels is crucial for high-risk patients or those on long-term therapy.
- Consider potential drug interactions, especially with cardiac medications and certain antibiotics.
Patient Guidelines
- Take as directed by your doctor.
- Do not exceed the recommended dose.
- Take with food for better absorption.
- Report any severe side effects to your doctor.
Missed Dose Advice
If a dose is missed, take it as soon as you remember. If it is almost time for the next dose, skip the missed dose and resume your regular dosing schedule. Do not double the dose.
Driving Precautions
Generally no specific precautions. Does not impair ability to drive or operate machinery.
Lifestyle Advice
- Maintain a balanced diet rich in calcium and vitamin D.
- Engage in regular weight-bearing exercise for bone health.
- Avoid excessive alcohol and smoking.
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Global Brand Names
International brand names for this medicine. Click a brand to search for detailed information.