Coralmax-D
Generic Name
Calcium Carbonate (from Coral Source) 1250 mg (equivalent to Elemental Calcium 500 mg) & Vitamin D3 200 IU Tablet
Manufacturer
Beximco Pharmaceuticals Ltd.
Country
Bangladesh
Loading images...
Price Details
Current market pricing information
| Variant | Unit Price | Strip Price |
|---|---|---|
| coralmax d 500 mg tablet | ৳ 11.00 | ৳ 110.00 |
Description
Overview of the medicine
Coralmax-D 500 mg Tablet is a nutritional supplement containing elemental calcium from coral sources and Vitamin D3 (Cholecalciferol). It is primarily used to maintain healthy bones, prevent osteoporosis, and treat conditions associated with calcium and Vitamin D deficiency.
Uses & Indications
Dosage
Adults
Typically, 1-2 tablets daily, preferably with meals, or as directed by a physician.
Elderly
Same as adults, with careful monitoring for renal function and hypercalcemia.
Renal_impairment
Use with caution. Dosage adjustment may be required; consult a physician. Avoid in severe renal impairment.
How to Take
For oral use. Tablets should be swallowed whole with water, preferably after a meal to enhance absorption and reduce gastric upset.
Mechanism of Action
Calcium is an essential mineral for bone formation and maintenance, nerve transmission, muscle contraction, and blood coagulation. Vitamin D3 facilitates the absorption of calcium and phosphate from the gastrointestinal tract and regulates their metabolism, thereby promoting bone mineralization.
Pharmacokinetics
Onset
Clinical effects on bone mineral density are gradual, usually observed after weeks to months of consistent use.
Excretion
Calcium: Primarily excreted in feces, with a smaller amount via urine. Vitamin D3: Excreted via bile and feces.
Half life
Calcium: Varies depending on physiological needs; Vitamin D3: Approximately 15-20 days, but its metabolites can have longer half-lives.
Absorption
Calcium carbonate is absorbed from the gastrointestinal tract, with approximately 25-35% of elemental calcium being absorbed. Absorption is enhanced by Vitamin D. Vitamin D3 is well absorbed from the gastrointestinal tract in the presence of bile salts.
Metabolism
Calcium is primarily not metabolized but regulated. Vitamin D3 is hydroxylated in the liver to 25-hydroxyvitamin D (calcifediol) and then in the kidneys to 1,25-dihydroxyvitamin D (calcitriol), the active form.
Side Effects
Contraindications
- Hypersensitivity to any component
- Hypercalcemia (high blood calcium levels)
- Severe hypercalciuria (excessive calcium in urine)
- Nephrolithiasis (kidney stones)
- Severe renal impairment
- Hyperparathyroidism
Drug Interactions
Bisphosphonates
Calcium can reduce absorption. Administer at least 30 minutes apart.
Corticosteroids
May decrease calcium absorption.
Thyroid hormones
Calcium may reduce absorption of levothyroxine. Take at least 4 hours apart.
Cardiac glycosides
Hypercalcemia may increase the risk of cardiac arrhythmias.
Thiazide diuretics
May increase the risk of hypercalcemia.
Tetracyclines & Quinolones
Calcium can reduce the absorption of these antibiotics. Take calcium at least 2 hours before or 4-6 hours after.
Storage
Store in a cool, dry place, below 30°C. Protect from light and moisture. Keep out of reach of children.
Overdose
Symptoms of overdose include hypercalcemia (nausea, vomiting, constipation, thirst, polyuria, muscle weakness, bone pain, confusion). Treatment involves discontinuing the supplement, hydration, and medical management to lower calcium levels. Seek immediate medical attention.
Pregnancy & Lactation
Considered safe and often recommended during pregnancy and lactation to meet increased calcium and Vitamin D requirements. However, always consult a physician before use.
Side Effects
Contraindications
- Hypersensitivity to any component
- Hypercalcemia (high blood calcium levels)
- Severe hypercalciuria (excessive calcium in urine)
- Nephrolithiasis (kidney stones)
- Severe renal impairment
- Hyperparathyroidism
Drug Interactions
Bisphosphonates
Calcium can reduce absorption. Administer at least 30 minutes apart.
Corticosteroids
May decrease calcium absorption.
Thyroid hormones
Calcium may reduce absorption of levothyroxine. Take at least 4 hours apart.
Cardiac glycosides
Hypercalcemia may increase the risk of cardiac arrhythmias.
Thiazide diuretics
May increase the risk of hypercalcemia.
Tetracyclines & Quinolones
Calcium can reduce the absorption of these antibiotics. Take calcium at least 2 hours before or 4-6 hours after.
Storage
Store in a cool, dry place, below 30°C. Protect from light and moisture. Keep out of reach of children.
Overdose
Symptoms of overdose include hypercalcemia (nausea, vomiting, constipation, thirst, polyuria, muscle weakness, bone pain, confusion). Treatment involves discontinuing the supplement, hydration, and medical management to lower calcium levels. Seek immediate medical attention.
Pregnancy & Lactation
Considered safe and often recommended during pregnancy and lactation to meet increased calcium and Vitamin D requirements. However, always consult a physician before use.
Frequently Asked Questions
Common questions about this medicine
Pack Sizes
Shelf Life
24 months from the date of manufacture
Availability
Pharmacies, Drugstores, Hospitals
Approval Status
Approved by DGDA (Directorate General of Drug Administration, Bangladesh)
Patent Status
Not Applicable / Expired
Clinical Trials
Extensive clinical data support the efficacy of calcium and vitamin D supplementation in preventing and treating osteoporosis and deficiencies.
Lab Monitoring
- Serum calcium levels (especially in long-term use or renal impairment)
- Serum Vitamin D levels
- Renal function (creatinine, eGFR)
Doctor Notes
- Advise patients to maintain adequate hydration.
- Caution in patients with a history of kidney stones or impaired renal function.
- Monitor serum calcium and vitamin D levels periodically in high-risk patients.
Patient Guidelines
- Take as directed by your physician or pharmacist.
- Do not exceed the recommended dose.
- Maintain adequate fluid intake.
- Inform your doctor about all other medications you are taking.
- Report any unusual or severe side effects to your doctor immediately.
Missed Dose Advice
If a dose is missed, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for a missed one.
Driving Precautions
Coralmax-D 500 mg Tablet is not known to affect the ability to drive or operate machinery.
Lifestyle Advice
- Regular weight-bearing exercise is beneficial for bone health.
- Maintain a balanced diet rich in calcium and Vitamin D.
- Quit smoking and limit alcohol intake, as they can negatively affect bone density.
Alternative Medicines in Bangladesh
Similar medicines available in the market
Global Brand Names
International brand names for this medicine. Click a brand to search for detailed information.