Coralvit-DX
Generic Name
Calcium Carbonate (elemental) 600 mg + Vitamin D3 400 IU
Manufacturer
Square Pharmaceuticals Ltd.
Country
Bangladesh
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Price Details
Current market pricing information
| Variant | Unit Price | Strip Price |
|---|---|---|
| coralvit dx 600 mg tablet | ৳ 16.00 | ৳ 160.00 |
Description
Overview of the medicine
Coralvit-DX 600 mg Tablet is a combination medicine containing elemental Calcium and Vitamin D3. It is primarily used to prevent and treat calcium and vitamin D deficiencies, promoting bone health.
Uses & Indications
Dosage
Adults
1 tablet once or twice daily, or as directed by the physician.
Elderly
Same as adult dosage, but caution with renal function.
Renal_impairment
Use with caution and monitor calcium/phosphate levels. Dose adjustment may be necessary in severe cases.
How to Take
Oral. Can be taken with or without food. For best absorption, it's often advised to take with meals. Do not crush or chew if not a chewable tablet.
Mechanism of Action
Calcium is an essential mineral for bone formation, nerve transmission, muscle contraction, and blood coagulation. Vitamin D3 helps the body absorb calcium from the gastrointestinal tract and regulates calcium and phosphate levels, crucial for bone mineralization.
Pharmacokinetics
Onset
Gradual, as it involves bone remodeling and mineral replenishment.
Excretion
Calcium is primarily excreted via urine and feces. Vitamin D metabolites are excreted mainly in bile and feces.
Half life
Calcium's physiological half-life is complex; Vitamin D3's half-life is about 15-20 days.
Absorption
Calcium absorption varies and is influenced by vitamin D levels. Vitamin D3 is well absorbed from the GI tract.
Metabolism
Calcium is not metabolized in the traditional sense. Vitamin D3 is hydroxylated in the liver to 25-hydroxyvitamin D [25(OH)D] and then in the kidneys to the active form 1,25-dihydroxyvitamin D [1,25(OH)2D].
Side Effects
Contraindications
- •Hypersensitivity to any component
- •Hypercalcaemia
- •Hypercalciuria
- •Severe renal impairment
- •Nephrolithiasis (kidney stones)
- •Hypervitaminosis D
Drug Interactions
Levothyroxine
Reduced absorption of levothyroxine. Separate administration times.
Bisphosphonates
Reduced absorption. Separate administration times.
Iron supplements
Reduced iron absorption. Separate administration times.
Cardiac glycosides
Increased risk of arrhythmias.
Thiazide diuretics
May increase risk of hypercalcaemia.
Tetracyclines & Quinolones
Calcium may reduce absorption. Take calcium several hours before or after.
Storage
Store in a cool, dry place below 30°C. Protect from light and moisture. Keep out of reach of children.
Overdose
Symptoms of overdose include hypercalcaemia (nausea, vomiting, constipation, thirst, polyuria, muscle weakness), hypervitaminosis D. Treatment involves discontinuing the product, hydration, and medical management of hypercalcaemia.
Pregnancy & Lactation
Generally considered safe and often recommended during pregnancy and lactation to meet increased calcium and vitamin D needs, but only under medical supervision. Do not exceed recommended doses.
Frequently Asked Questions
Common questions about this medicine
Pack Sizes
Shelf Life
24 months from manufacturing date.
Availability
Pharmacies nationwide
Approval Status
Approved by DGDA
Patent Status
Generic
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Global Brand Names
International brand names for this medicine
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