Cutisone
Generic Name
Topical Corticosteroid 0.05%
Manufacturer
Hypothetical Pharma Co. Ltd.
Country
Bangladesh
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Price Details
Current market pricing information
Variant | Unit Price | Strip Price |
---|---|---|
cutisone 0005 ointment | ৳ 50.35 | N/A |
Description
Overview of the medicine
Cutisone 0.05% Ointment is a low-potency topical corticosteroid used to reduce inflammation, itching, and redness associated with various skin conditions.
Uses & Indications
Dosage
Adults
Apply a thin film to the affected skin area once or twice daily. Do not use for more than 2-4 weeks without medical review.
Elderly
Same as adults; use with caution due to thinner skin.
Renal_impairment
No dosage adjustment necessary for topical use.
How to Take
For topical use only. Apply a thin layer to the affected skin area and rub in gently. Wash hands before and after application. Avoid contact with eyes, mouth, and other mucous membranes.
Mechanism of Action
Topical corticosteroids work by inducing phospholipase A2 inhibitory proteins, thereby controlling the biosynthesis of potent mediators of inflammation such as prostaglandins and leukotrienes. They also exhibit immunosuppressive and antiproliferative actions.
Pharmacokinetics
Onset
Within hours to days of application.
Excretion
Systemically absorbed portions are excreted primarily via the kidneys.
Half life
Local effect is sustained; systemically absorbed drug metabolized quickly.
Absorption
Minimal systemic absorption through intact skin. Absorption increases with skin damage, occlusion, or application to large surface areas.
Metabolism
Primarily metabolized in the skin, with some systemic metabolism in the liver if significant absorption occurs.
Side Effects
Contraindications
- Hypersensitivity to the active substance or any excipients
- Untreated cutaneous infections (viral, fungal, bacterial, parasitic)
- Acne vulgaris, rosacea, perioral dermatitis
- Pruritus without inflammation
Drug Interactions
Immunosuppressants
May enhance immunosuppressive effects.
Systemic Corticosteroids
Increased risk of systemic effects if significant absorption occurs.
Storage
Store below 30°C, protected from light and moisture. Do not freeze. Keep out of reach of children.
Overdose
Acute overdose is unlikely with topical application. Chronic overdose or misuse (e.g., prolonged use over large areas, under occlusion) can lead to local side effects (skin atrophy) or systemic effects (adrenal suppression).
Pregnancy & Lactation
Use during pregnancy and lactation only if the potential benefit justifies the potential risk to the fetus or infant. Consult a doctor.
Frequently Asked Questions
Common questions about this medicine
Pack Sizes
Shelf Life
24 to 36 months from manufacturing date.
Availability
Available in pharmacies
Approval Status
Approved in various countries
Patent Status
Generally off-patent for common corticosteroids
Clinical Trials
As a generic low-potency corticosteroid, extensive new clinical trials are generally not required, but bioequivalence studies may be conducted for generic formulations.
Lab Monitoring
- Not routinely required for localized, short-term topical use. In cases of extensive or prolonged use, monitoring for adrenal suppression (e.g., plasma cortisol levels) may be considered.
Doctor Notes
- Advise patients on appropriate application technique and duration of use.
- Educate on potential side effects, particularly with prolonged use or improper application.
- Consider step-down therapy or intermittent use to minimize risks.
Patient Guidelines
- Use only as directed by your doctor.
- Apply a thin layer; do not use excessive amounts.
- Do not cover the treated area with bandages or occlusive dressings unless advised by a doctor.
- Avoid contact with eyes and mucous membranes.
- Wash hands before and after application.
Missed Dose Advice
If you miss a dose, apply it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not apply a double dose.
Driving Precautions
Cutisone 0.05% Ointment has no known effect on the ability to drive or operate machinery.
Lifestyle Advice
- Keep affected skin clean and moisturized.
- Avoid known irritants or allergens that trigger your skin condition.
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Global Brand Names
International brand names for this medicine. Click a brand to search for detailed information.