Cyclovex-3 Eye Ointment
Generic Name
Acyclovir Ophthalmic Ointment
Manufacturer
Beximco Pharmaceuticals Ltd.
Country
Bangladesh
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Price Details
Current market pricing information
| Variant | Unit Price | Strip Price |
|---|---|---|
| cyclovex 3 eye ointment | ৳ 55.00 | N/A |
Description
Overview of the medicine
Cyclovex-3 Eye Ointment contains Acyclovir, an antiviral agent, used to treat eye infections caused by the herpes simplex virus.
Uses & Indications
Dosage
Adults
Apply a 1 cm ribbon of ointment into the lower conjunctival sac 5 times daily at approximately 4-hour intervals while awake. Continue treatment for 14 days or until healing is complete.
Elderly
No specific dosage adjustment required.
Renal_impairment
Not applicable for topical ophthalmic use due to minimal systemic absorption.
How to Take
For ophthalmic use only. Wash hands before and after application. Pull down the lower eyelid, apply a thin strip of ointment into the conjunctival sac. Close eye gently for a few moments. Do not touch the tip of the tube to the eye or any other surface.
Mechanism of Action
Acyclovir is a synthetic purine nucleoside analogue that inhibits viral DNA replication by competitive inhibition of viral DNA polymerase, ultimately terminating the DNA chain.
Pharmacokinetics
Onset
Local antiviral effect observed within hours, clinical improvement typically within days.
Excretion
Primarily local clearance; negligible systemic excretion.
Half life
Not clinically significant for topical ophthalmic use due to minimal systemic absorption (systemic half-life 2.5-3.3 hours).
Absorption
Minimal systemic absorption from ophthalmic application. Primarily acts locally.
Metabolism
Minimal systemic metabolism. Locally converted to active triphosphate form.
Side Effects
Contraindications
- Hypersensitivity to Acyclovir, Valacyclovir, or any component of the formulation.
- Patients with known allergy to similar antiviral agents.
Drug Interactions
Systemic drugs
Due to minimal systemic absorption, clinically significant drug interactions are unlikely with systemic medications.
Storage
Store below 25°C, protected from light and moisture. Do not freeze. Keep out of reach of children.
Overdose
Due to minimal systemic absorption, overdose from topical ophthalmic application is unlikely to cause systemic toxicity. If accidentally ingested, seek medical advice.
Pregnancy & Lactation
Use during pregnancy or lactation should only be considered if the potential benefit to the mother outweighs the potential risk to the fetus or infant. Consult a doctor before use.
Frequently Asked Questions
Common questions about this medicine
Pack Sizes
Shelf Life
24-36 months (unopened). Discard 28 days after opening.
Availability
Pharmacies, Hospitals
Approval Status
DGDA Approved
Patent Status
Off-patent (Generic)
WHO Essential Medicine
YesClinical Trials
Acyclovir's efficacy and safety for herpes simplex keratitis have been established through extensive clinical trials. Post-marketing surveillance continues to monitor its long-term effects.
Lab Monitoring
- No specific laboratory monitoring is generally required for topical ophthalmic acyclovir.
Doctor Notes
- Ensure patients understand the importance of completing the full course to prevent recurrence and resistance.
- Advise patients on proper application technique and hygiene to avoid contamination.
- Monitor for signs of secondary bacterial or fungal infection if symptoms persist or worsen.
Patient Guidelines
- Complete the full course of treatment as prescribed, even if symptoms improve.
- Do not wear contact lenses during treatment for herpes simplex keratitis.
- Avoid touching the eye or the tip of the ointment tube to prevent contamination.
- If symptoms worsen or do not improve after recommended treatment duration, consult your doctor.
Missed Dose Advice
If a dose is missed, apply it as soon as you remember. If it is almost time for the next dose, skip the missed dose and resume your regular dosing schedule. Do not apply a double dose to make up for a missed one.
Driving Precautions
Cyclovex-3 Eye Ointment may cause temporary blurred vision immediately after application. Avoid driving or operating machinery until your vision clears.
Lifestyle Advice
- Maintain good eye hygiene to prevent further irritation or infection.
- Avoid sharing towels, pillows, or eye makeup to prevent spreading the infection.
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Global Brand Names
International brand names for this medicine. Click a brand to search for detailed information.