Take Dacocent 45 mg tablet orally, once daily, with or without food. Swallow the tablet whole; do not crush, chew, or divide.

Dacocent acts as a potent inhibitor of serotonin and norepinephrine reuptake in the central nervous system. This dual action increases the synaptic concentrations of these neurotransmitters, which is believed to contribute to its antidepressant and anxiolytic effects. It also has minor effects on dopamine reuptake.

• •Hypersensitivity to dacoxetine or any component of the formulation.
• •Concomitant use with Monoamine Oxidase Inhibitors (MAOIs) or within 14 days of discontinuing an MAOI.
• •Uncontrolled narrow-angle glaucoma.
• •Severe uncontrolled hypertension.

Store below 30°C, away from moisture and direct light. Keep out of reach of children.

Symptoms may include somnolence, coma, seizures, tachycardia, hypertension, vomiting, and serotonin syndrome. Management involves symptomatic and supportive treatment, including airway management, monitoring of cardiac and vital signs, and activated charcoal. There is no specific antidote.

Pregnancy Category C. Should be used during pregnancy only if the potential benefit justifies the potential risk to the fetus. Neonates exposed to SNRIs late in the third trimester have developed complications requiring prolonged hospitalization, respiratory support, and tube feeding. Dacoxetine is excreted into breast milk. A decision should be made whether to discontinue nursing or to discontinue the drug, taking into account the importance of the drug to the mother.