Dakrin
Generic Name
Desloratadine
Manufacturer
Square Pharmaceuticals Ltd.
Country
Bangladesh
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Price Details
Current market pricing information
| Variant | Unit Price | Strip Price |
|---|---|---|
| dakrin 2 w oral gel | ৳ 90.00 | N/A |
Description
Overview of the medicine
Dakrin 5 mg Tablet contains Desloratadine, an antihistamine that provides rapid relief from allergy symptoms such as sneezing, runny nose, itchy eyes, and hives. It is a non-drowsy formulation.
Uses & Indications
Dosage
Adults
One 5 mg tablet once daily.
Elderly
No dosage adjustment generally required.
Renal_impairment
For severe renal impairment, consider administering every other day.
How to Take
For oral use. Can be taken with or without food.
Mechanism of Action
Desloratadine is a potent, selective, peripherally acting histamine H1-receptor antagonist. It inhibits the release of histamine from mast cells and basophils.
Pharmacokinetics
Onset
Within 30 minutes
Excretion
Primarily excreted in urine and feces as metabolites.
Half life
Approximately 27 hours
Absorption
Rapidly absorbed after oral administration. Peak plasma concentrations are reached in approximately 3 hours.
Metabolism
Extensively metabolized to 3-hydroxydesloratadine, an active metabolite.
Side Effects
Contraindications
- Hypersensitivity to Desloratadine, Loratadine, or any component of the formulation
Drug Interactions
Cimetidine
Increased plasma concentration of Desloratadine.
Erythromycin
Increased plasma concentration of Desloratadine.
Ketoconazole
Increased plasma concentration of Desloratadine.
Storage
Store in a cool, dry place, away from light and moisture. Keep out of reach of children.
Overdose
In case of overdose, symptomatic and supportive treatment should be initiated. Desloratadine is not effectively removed by hemodialysis.
Pregnancy & Lactation
Pregnancy Category C. Use only if potential benefit justifies potential risk to the fetus. Not recommended during breastfeeding as Desloratadine is excreted in breast milk.
Frequently Asked Questions
Common questions about this medicine
Pack Sizes
Shelf Life
3 years
Availability
Available in all pharmacies
Approval Status
Approved by DGDA
Patent Status
Patent expired
Clinical Trials
Desloratadine has undergone extensive clinical trials demonstrating its efficacy and safety for allergic conditions.
Lab Monitoring
- No specific lab monitoring generally required.
Doctor Notes
- Advise patients to take Dakrin consistently for optimal relief.
- Remind patients that it is a non-sedating antihistamine for most.
Patient Guidelines
- Take as directed by your doctor.
- Do not exceed the recommended dose.
- Inform your doctor about all other medications you are taking.
Missed Dose Advice
If a dose is missed, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and resume your regular dosing schedule. Do not take a double dose.
Driving Precautions
Although considered non-drowsy, individual responses may vary. Caution is advised when driving or operating machinery until you know how Dakrin affects you.
Lifestyle Advice
- Avoid known allergens that trigger your symptoms.
- Maintain good hygiene to reduce allergen exposure.
Alternative Medicines in Bangladesh
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Global Brand Names
International brand names for this medicine. Click a brand to search for detailed information.