Deep Heat
Generic Name
Methyl Salicylate and Menthol Cream
Manufacturer
Mentholatum Company
Country
United Kingdom
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Price Details
Current market pricing information
| Variant | Unit Price | Strip Price |
|---|---|---|
| deep heat 30 8 cream | ৳ 90.00 | N/A |
Description
Overview of the medicine
Deep Heat 30-8 Cream is a warming, topical analgesic cream used for the temporary relief of muscular aches, stiffness, sprains, and rheumatic pain. It contains methyl salicylate and menthol which work together to provide pain relief and a warming sensation.
Uses & Indications
Dosage
Adults
Apply thinly and gently massage into the affected area until absorbed, 2-3 times daily.
Elderly
No special dosage recommendations; use as for adults, with caution for sensitive skin.
Renal_impairment
No specific dosage adjustment required for topical application. Avoid extensive use in severe renal impairment.
How to Take
For external use only. Apply a small amount to the affected area and gently massage until fully absorbed. Wash hands thoroughly after use.
Mechanism of Action
Methyl salicylate is a topical non-steroidal anti-inflammatory drug (NSAID) that acts locally to reduce pain and inflammation. Menthol is a counterirritant that first produces a cooling sensation, followed by a warming effect, which helps to distract from pain and increase blood flow to the affected area.
Pharmacokinetics
Onset
Within minutes to 15-30 minutes after application.
Excretion
Metabolites of both compounds are primarily excreted renally.
Half life
Not well-defined for topical application; systemic half-life of salicylate is 2-4.5 hours.
Absorption
Both methyl salicylate and menthol are absorbed through the skin, with peak plasma levels typically occurring several hours after application. Systemic absorption is generally low with topical application.
Metabolism
Methyl salicylate is hydrolyzed to salicylic acid. Menthol is primarily metabolized in the liver via glucuronidation.
Side Effects
Contraindications
- •Hypersensitivity to salicylates, menthol, or any other ingredients.
- •Broken, irritated, or sensitive skin.
- •Not to be used on eyes or mucous membranes.
- •Children under 5 years of age.
- •Asthma patients sensitive to salicylates (rare for topical).
Drug Interactions
Other topical medications
Avoid applying other topical pain relievers or creams to the same area simultaneously to prevent additive irritation.
Warfarin (oral anticoagulants)
High doses or extensive topical use of methyl salicylate may increase the risk of bleeding in patients taking warfarin due to systemic absorption, though this is rare with normal use.
Storage
Store below 25°C. Do not freeze. Keep out of reach of children. Protect from direct sunlight.
Overdose
Overdose is unlikely with topical application. Excessive use or ingestion could lead to salicylate toxicity (nausea, vomiting, tinnitus) or menthol toxicity (abdominal pain, CNS depression). Seek medical attention if ingested or severe reactions occur.
Pregnancy & Lactation
Consult a doctor or pharmacist before use during pregnancy or breastfeeding, especially if applying to large areas or for prolonged periods. Use with caution.
Frequently Asked Questions
Common questions about this medicine
Pack Sizes
Shelf Life
Typically 2-3 years from manufacturing date.
Availability
Pharmacies, supermarkets, general stores
Approval Status
Approved (Over-the-Counter)
Patent Status
Off-patent
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