Delameg
Generic Name
Megestrol Acetate
Manufacturer
Reputable Pharmaceutical Co.
Country
Bangladesh
Loading images...
Price Details
Current market pricing information
| Variant | Unit Price | Strip Price |
|---|---|---|
| delameg 300 mg injection | ৳ 1,700.00 | N/A |
Description
Overview of the medicine
Megestrol Acetate is a synthetic progestin used as an appetite stimulant in cachexia (wasting syndrome) related to AIDS or cancer, and for palliative treatment of advanced breast or endometrial cancer.
Uses & Indications
Dosage
Adults
For anorexia/cachexia: Typically 300 mg once daily by intramuscular or subcutaneous injection, or as directed by physician. For cancer: Doses vary, consult physician.
Elderly
Dosage adjustments usually not required based on age alone, but monitor renal/hepatic function.
Renal_impairment
Use with caution. Specific recommendations may vary; generally, lower doses or extended intervals may be needed.
How to Take
Administer intramuscularly or subcutaneously as directed by a healthcare professional. Do not administer intravenously.
Mechanism of Action
The exact mechanism for appetite stimulation is unknown but thought to involve metabolic pathways. For cancer, it's believed to exert anti-estrogenic effects and direct cytotoxic effects on tumor cells.
Pharmacokinetics
Onset
Appetite stimulation may take several weeks.
Excretion
Primarily through urine, some via feces.
Half life
Approximately 13-16 hours.
Absorption
Well absorbed; for injection, direct systemic absorption.
Metabolism
Primarily hepatic (liver) metabolism.
Side Effects
Contraindications
- •Hypersensitivity to megestrol acetate or any component of the formulation.
- •Known or suspected pregnancy.
Drug Interactions
Warfarin
Increased INR/bleeding risk.
Indinavir
May decrease indinavir levels.
Rifabutin, Rifampicin
May decrease megestrol levels.
Storage
Store at room temperature (20-25°C), protect from light. Do not freeze.
Overdose
No specific antidote. Supportive care and symptomatic treatment should be provided.
Pregnancy & Lactation
Contraindicated during pregnancy due to potential fetal harm. Not recommended during lactation as it may be excreted in breast milk.
Frequently Asked Questions
Common questions about this medicine
Pack Sizes
Shelf Life
24 months
Availability
Pharmacies, Hospitals
Approval Status
Approved
Patent Status
Off-patent
Alternative Medicines in Bangladesh
Similar medicines available in the market
Global Brand Names
International brand names for this medicine
More Medicines
Explore other medicines you might be interested in