Dermocin-2-W
Generic Name
Mometasone Furoate Topical
Manufacturer
XYZ Pharmaceuticals Ltd.
Country
Bangladesh
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Price Details
Current market pricing information
| Variant | Unit Price | Strip Price |
|---|---|---|
| dermocin 2 w ointment | ৳ 130.00 | N/A |
Description
Overview of the medicine
Dermocin-2-W Ointment contains Mometasone Furoate, a potent synthetic corticosteroid for topical dermatologic use. It is primarily used to relieve the inflammatory and pruritic manifestations of corticosteroid-responsive dermatoses.
Uses & Indications
Dosage
Adults
Apply a thin film of ointment to the affected skin areas once daily.
Elderly
No specific dosage adjustments required; use with caution due to thinner skin.
Renal_impairment
No specific dosage adjustments required.
How to Take
For external use only. Apply a thin layer to the affected skin area and gently rub in. Wash hands thoroughly before and after application.
Mechanism of Action
Mometasone Furoate is a corticosteroid that primarily acts as an anti-inflammatory, antipruritic, and vasoconstrictive agent. It inhibits the release of arachidonic acid metabolites, stabilizes lysosomal membranes, and decreases leukocyte migration, thereby reducing inflammation and associated symptoms.
Pharmacokinetics
Onset
Anti-inflammatory effects usually begin within hours of application.
Excretion
Metabolites are excreted via urine and feces.
Half life
Not well-defined for topical application due to minimal systemic absorption; systemic half-life of absorbed drug is about 5.8 hours.
Absorption
Minimal systemic absorption occurs when applied topically, typically less than 0.7% of the applied dose, but it can be increased by occlusion or application to damaged skin.
Metabolism
Absorbed mometasone furoate is rapidly metabolized in the liver.
Side Effects
Contraindications
- Hypersensitivity to Mometasone Furoate or any component of the ointment.
- Untreated cutaneous viral, bacterial, or fungal infections.
- Rosacea, perioral dermatitis, acne vulgaris, perianal and genital pruritus.
Drug Interactions
Immunosuppressants
May enhance systemic absorption and effect, especially with extensive use.
Other topical corticosteroids
Concurrent use should be avoided to prevent additive systemic effects.
Storage
Store below 30°C. Protect from light and moisture. Keep out of reach of children.
Overdose
Topical overdose is unlikely to cause acute toxicity. Prolonged or excessive use may lead to systemic effects such as Cushing's syndrome or HPA axis suppression. Treatment is symptomatic and supportive.
Pregnancy & Lactation
Use during pregnancy only if the potential benefit justifies the potential risk to the fetus. Caution should be exercised when administered to a nursing woman. Consult a doctor.
Side Effects
Contraindications
- Hypersensitivity to Mometasone Furoate or any component of the ointment.
- Untreated cutaneous viral, bacterial, or fungal infections.
- Rosacea, perioral dermatitis, acne vulgaris, perianal and genital pruritus.
Drug Interactions
Immunosuppressants
May enhance systemic absorption and effect, especially with extensive use.
Other topical corticosteroids
Concurrent use should be avoided to prevent additive systemic effects.
Storage
Store below 30°C. Protect from light and moisture. Keep out of reach of children.
Overdose
Topical overdose is unlikely to cause acute toxicity. Prolonged or excessive use may lead to systemic effects such as Cushing's syndrome or HPA axis suppression. Treatment is symptomatic and supportive.
Pregnancy & Lactation
Use during pregnancy only if the potential benefit justifies the potential risk to the fetus. Caution should be exercised when administered to a nursing woman. Consult a doctor.
Frequently Asked Questions
Common questions about this medicine
Pack Sizes
Shelf Life
24 months from the date of manufacture
Availability
Available in pharmacies nationwide
Approval Status
Approved by regulatory authorities worldwide
Patent Status
Off-patent
Clinical Trials
Mometasone Furoate has undergone extensive clinical trials demonstrating its efficacy and safety in various corticosteroid-responsive dermatoses. Studies have shown it to be effective with a favorable safety profile when used as directed.
Lab Monitoring
- Routine lab monitoring is not typically required for topical use. HPA axis suppression may be assessed with urinary free cortisol test or ACTH stimulation test in cases of extensive or prolonged use.
Doctor Notes
- Advise patients on appropriate application technique and duration of use.
- Emphasize the importance of avoiding use on the face, groin, and axillae unless specifically indicated.
- Monitor for signs of local skin reactions or systemic absorption with prolonged or extensive use.
Patient Guidelines
- Apply thinly and sparingly to the affected area.
- Do not use on the face, groin, or axillae unless directed by a doctor.
- Avoid contact with eyes. If contact occurs, rinse thoroughly with water.
- Do not cover the treated area with occlusive dressings unless advised by a physician.
Missed Dose Advice
If a dose is missed, apply it as soon as remembered. If it is almost time for the next dose, skip the missed dose and resume the regular dosing schedule. Do not apply a double dose.
Driving Precautions
Dermocin-2-W Ointment has no known effect on the ability to drive or operate machinery.
Lifestyle Advice
- Maintain good skin hygiene to prevent further infections. Avoid prolonged exposure to direct sunlight on treated areas.
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Global Brand Names
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