Dinosen
Generic Name
Dinosen
Manufacturer
Aarong Pharma Ltd.
Country
Bangladesh
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Price Details
Current market pricing information
| Variant | Unit Price | Strip Price |
|---|---|---|
| dinosen 2 mg tablet | ৳ 50.00 | ৳ 500.00 |
Description
Overview of the medicine
Dinosen 2 mg Tablet is an antihistamine primarily used to relieve symptoms of allergies such as runny nose, sneezing, itchy or watery eyes, and itching of the skin. It can also be used to treat insomnia and motion sickness due to its sedative properties.
Uses & Indications
Dosage
Adults
Adults: 2 mg (1 tablet) taken orally, 2-3 times daily, or as directed by physician. For insomnia, 2 mg at bedtime.
Elderly
Elderly: Lower doses may be required due to increased sensitivity and potential for adverse effects. Start with 2 mg once daily, preferably at bedtime.
Renal_impairment
Renal impairment: No specific dosage adjustment usually needed, but caution advised. Consider longer dosing intervals or reduced dose if severe impairment.
How to Take
Take Dinosen 2 mg Tablet orally with a glass of water, with or without food. Do not crush or chew the tablet. For insomnia, take it 30 minutes before bedtime.
Mechanism of Action
Dinosen acts as a first-generation H1-receptor antagonist. It competitively blocks histamine H1 receptors, thereby preventing histamine from binding to these receptors and reducing the effects of histamine such as vasodilation, increased capillary permeability, and itching. It also has significant anticholinergic and sedative effects due to its ability to cross the blood-brain barrier.
Pharmacokinetics
Onset
Within 15-30 minutes for antihistaminic effects; sedation may occur sooner.
Excretion
Excreted mainly in the urine as metabolites within 24 hours; a small amount is excreted unchanged.
Half life
Approximately 4-8 hours in adults, but can vary.
Absorption
Readily absorbed from the gastrointestinal tract; peak plasma concentrations reached within 1-4 hours.
Metabolism
Primarily metabolized in the liver by the cytochrome P450 system (e.g., CYP2D6) to various inactive metabolites.
Side Effects
Contraindications
- Hypersensitivity to Dinosen or any component of the formulation
- Neonates and premature infants
- Nursing mothers
- Patients with acute asthma attacks
- Closed-angle glaucoma, urinary retention, prostatic hypertrophy
Drug Interactions
MAO Inhibitors
May prolong and intensify the anticholinergic effects of Dinosen.
CNS Depressants (e.g., alcohol, sedatives, hypnotics)
Concurrent use may enhance the sedative effects of Dinosen.
Anticholinergic drugs (e.g., tricyclic antidepressants, atropine)
Additive anticholinergic effects and increased risk of side effects like dry mouth, blurred vision, urinary retention.
Storage
Store in a cool, dry place, below 30°C. Protect from light and moisture. Keep out of reach of children.
Overdose
Symptoms of overdose may include severe drowsiness, blurred vision, dry mouth, flushing, fever, hallucinations, convulsions, and coma. Management involves symptomatic and supportive measures. Gastric lavage and activated charcoal may be considered if taken recently. Do not induce vomiting.
Pregnancy & Lactation
Pregnancy Category B. Use only if clearly needed and the benefit outweighs the risk. Dinosen is excreted in breast milk and may cause adverse effects in nursing infants; therefore, it is contraindicated in nursing mothers.
Frequently Asked Questions
Common questions about this medicine
Pack Sizes
Shelf Life
36 months from manufacturing date.
Availability
Pharmacies nationwide in Bangladesh
Approval Status
Approved by DGDA
Patent Status
Generic
WHO Essential Medicine
YesClinical Trials
Dinosen (assuming Diphenhydramine) has undergone numerous clinical trials demonstrating its efficacy and safety for allergic conditions, insomnia, and motion sickness. Specific trials for Dinosen 2 mg formulation by Aarong Pharma Ltd. would confirm local bioequivalence and stability.
Lab Monitoring
- No routine laboratory monitoring is typically required for Dinosen.
Doctor Notes
- Advise patients on potential sedative effects and caution regarding driving/operating machinery.
- Assess for underlying conditions (e.g., glaucoma, prostatic hypertrophy) before prescribing due to anticholinergic effects.
- Not recommended for long-term use in elderly due to increased risk of cognitive decline.
Patient Guidelines
- Avoid driving or operating heavy machinery until you know how this medicine affects you due to potential drowsiness.
- Avoid alcohol while taking Dinosen.
- Inform your doctor about all other medications you are taking, including over-the-counter drugs and herbal supplements.
Missed Dose Advice
If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and resume your regular dosing schedule. Do not double the dose to catch up.
Driving Precautions
Dinosen can cause drowsiness, dizziness, and blurred vision, which may impair your ability to drive or operate machinery. Avoid such activities until you are certain you can perform them safely.
Lifestyle Advice
- Maintain a consistent sleep schedule to improve sleep quality.
- Stay hydrated to help manage dry mouth.
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Global Brand Names
International brand names for this medicine. Click a brand to search for detailed information.