Dizmo
Generic Name
Dimenhydrinate
Manufacturer
Generic Pharmaceutical Company
Country
Global
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Price Details
Current market pricing information
| Variant | Unit Price | Strip Price |
|---|---|---|
| dizmo 50 mg tablet | ৳ 5.00 | ৳ 50.00 |
Description
Overview of the medicine
Dimenhydrinate is an antihistamine used to prevent and treat nausea, vomiting, and dizziness associated with motion sickness.
Uses & Indications
Dosage
Adults
50-100 mg every 4-6 hours as needed, not to exceed 400 mg in 24 hours.
Elderly
May require lower doses due to increased sensitivity to anticholinergic effects.
Renal_impairment
No specific dosage adjustment provided; use with caution.
How to Take
Oral administration. Take with water, with or without food. For motion sickness, take 30-60 minutes before travel.
Mechanism of Action
Dimenhydrinate acts as a competitive antagonist of H1 histamine receptors, particularly in the vestibular system, which helps to reduce the symptoms of motion sickness. It also has anticholinergic effects that contribute to its antiemetic action.
Pharmacokinetics
Onset
Typically within 15-30 minutes.
Excretion
Primarily excreted in the urine as metabolites.
Half life
Approximately 1-4 hours.
Absorption
Readily absorbed from the gastrointestinal tract.
Metabolism
Extensively metabolized in the liver.
Side Effects
Contraindications
- Hypersensitivity to dimenhydrinate or other antihistamines
- Acute angle-closure glaucoma
- Prostatic hypertrophy with urinary retention
Drug Interactions
Anticholinergic drugs
Increased risk of anticholinergic side effects (e.g., dry mouth, blurred vision, urinary retention).
Alcohol and CNS depressants
May enhance sedative effects.
Storage
Store in a cool, dry place, below 30°C. Protect from light and moisture. Keep out of reach of children.
Overdose
Symptoms include drowsiness, ataxia, convulsions, coma, respiratory depression, hallucinations, and dilated pupils. Treatment is supportive, including gastric lavage, activated charcoal, and symptomatic management.
Pregnancy & Lactation
Pregnancy Category B. Use only if clearly needed. Excreted in breast milk; use with caution during lactation.
Frequently Asked Questions
Common questions about this medicine
Pack Sizes
Shelf Life
Typically 2-3 years from manufacturing date.
Availability
Pharmacies, drugstores
Approval Status
Approved by health authorities
Patent Status
Generic
WHO Essential Medicine
YesClinical Trials
Extensive clinical experience supports the use of dimenhydrinate for motion sickness and nausea. Older drug with well-established efficacy.
Lab Monitoring
- No specific routine lab monitoring required for typical use.
Doctor Notes
- Advise patients about potential drowsiness.
- Caution in patients with respiratory conditions (e.g., asthma) due to anticholinergic effects.
- May mask symptoms of ototoxicity caused by other drugs.
Patient Guidelines
- Do not drive or operate heavy machinery until you know how this medicine affects you.
- Avoid alcohol and other CNS depressants.
- Take 30-60 minutes before travel for motion sickness prevention.
Missed Dose Advice
If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and return to your regular dosing schedule. Do not take a double dose.
Driving Precautions
May cause drowsiness and dizziness; avoid driving or operating machinery.
Lifestyle Advice
- Stay hydrated.
- Eat light meals before travel if prone to motion sickness.
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Global Brand Names
International brand names for this medicine. Click a brand to search for detailed information.