DNS
Generic Name
Dextrose 5% in Sodium Chloride 0.9% Injection
Manufacturer
Various manufacturers (e.g., Beximco Pharma, Square Pharma)
Country
Globally manufactured
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Price Details
Current market pricing information
| Variant | Unit Price | Strip Price |
|---|---|---|
| dns 09 5 injection | ৳ 75.67 | N/A |
Description
Overview of the medicine
DNS-09-5 Injection is a sterile, nonpyrogenic solution for intravenous administration, containing 5% Dextrose (glucose) and 0.9% Sodium Chloride. It is primarily used to provide fluid, electrolytes, and calories.
Uses & Indications
Dosage
Adults
Dosage is individualized based on patient's age, weight, clinical condition, and fluid/electrolyte requirements. Typically administered intravenously at rates determined by a healthcare professional.
Elderly
Use with caution; dose may need to be adjusted based on renal function and fluid balance.
Renal_impairment
Use with extreme caution; dosage adjustment and careful monitoring of fluid and electrolyte balance are essential.
How to Take
Administer intravenously, typically into a large peripheral or central vein, using sterile equipment. The rate of infusion should be carefully controlled.
Mechanism of Action
Dextrose provides a source of calories and helps in protein sparing. Sodium Chloride provides essential electrolytes (sodium and chloride) and helps to maintain osmotic pressure and fluid balance. When administered intravenously, the solution expands the extracellular fluid volume and provides energy.
Pharmacokinetics
Onset
Immediate upon administration.
Excretion
Water, carbon dioxide, and excess electrolytes are excreted via kidneys.
Half life
Dextrose is metabolized rapidly. Sodium and chloride half-life varies based on physiological needs and renal function.
Absorption
Administered intravenously, hence 100% bioavailable.
Metabolism
Dextrose is metabolized to carbon dioxide and water. Sodium and chloride are not metabolized.
Side Effects
Contraindications
- •Hypersensitivity to any component
- •Hyperglycemia, uncontrolled diabetes mellitus
- •Severe renal failure with anuria
- •Congestive heart failure, pulmonary edema (risk of fluid overload)
- •Hypernatremia, metabolic alkalosis
Drug Interactions
Insulin
Dosage may need adjustment due to dextrose content.
Corticosteroids
May increase sodium retention and risk of edema.
Drugs excreted renally
Fluid administration may affect drug excretion.
Storage
Store at controlled room temperature (20-25°C). Do not freeze. Protect from excessive heat. Keep out of reach of children.
Overdose
Overdose can lead to fluid overload, electrolyte imbalances (hypernatremia, hypokalemia), hyperglycemia, and edema. Treatment involves discontinuing the infusion, supportive care, and correcting electrolyte imbalances.
Pregnancy & Lactation
Generally considered safe for use during pregnancy and lactation when clinically indicated and administered with appropriate monitoring.
Frequently Asked Questions
Common questions about this medicine
Pack Sizes
Shelf Life
Typically 2-3 years, refer to manufacturer's label.
Availability
Hospitals, Clinics, Pharmacies (for professional use)
Approval Status
Approved worldwide by regulatory bodies
Patent Status
Off-patent
WHO Essential Medicine
YesAlternative Medicines in Bangladesh
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Global Brand Names
International brand names for this medicine
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