Dobelit capsule should be taken orally, preferably with food or milk to minimize gastrointestinal upset. Swallow the capsule whole with a full glass of water. Do not chew, crush, or break the capsule.

Dobelit acts by inhibiting cyclooxygenase (COX) enzymes, particularly COX-1 and COX-2. This inhibition leads to a reduction in the synthesis of prostaglandins, which are key mediators of pain, inflammation, and fever.

• •Hypersensitivity to Dobelit or other NSAIDs
• •Active peptic ulcer or gastrointestinal bleeding
• •Severe renal or hepatic impairment
• •Severe heart failure
• •Third trimester of pregnancy
• •Asthma, urticaria, or allergic-type reactions after taking aspirin or other NSAIDs

Store in a cool, dry place below 30°C. Protect from light and moisture. Keep out of reach of children.

Symptoms of overdose may include drowsiness, nausea, vomiting, epigastric pain, lethargy, and gastrointestinal bleeding. Management involves symptomatic and supportive measures. Gastric lavage or activated charcoal may be considered if ingestion is recent.

Pregnancy Category C (first two trimesters), D (third trimester). Avoid in the third trimester due to potential premature closure of the fetal ductus arteriosus. Use with caution during lactation, as Dobelit may pass into breast milk.