e-lax
Generic Name
Polyethylene Glycol 3350
Manufacturer
Acme Pharmaceuticals
Country
Bangladesh
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Price Details
Current market pricing information
| Variant | Unit Price | Strip Price |
|---|---|---|
| e lax 335 gm oral solution | ৳ 100.00 | N/A |
Description
Overview of the medicine
e-lax-335-gm-oral-solution is an osmotic laxative containing Polyethylene Glycol 3350, used for the treatment of occasional or chronic constipation. It works by retaining water in the stool, making it softer and easier to pass.
Uses & Indications
Dosage
Adults
The usual dose is 17 gm (one level scoop or one packet) of powder dissolved in 120-240 mL (4-8 ounces) of water or other beverage, taken once daily. Do not exceed recommended dosage.
Elderly
No specific dose adjustment is usually required for elderly patients, same as adult dose.
Renal_impairment
No dose adjustment is typically needed for patients with renal impairment.
How to Take
Dissolve the prescribed amount of powder completely in 4 to 8 ounces (120-240 mL) of water, juice, soda, coffee, or tea. Drink the solution immediately. It can be taken with or without food.
Mechanism of Action
Polyethylene Glycol 3350 (PEG 3350) acts as an osmotic agent, drawing water into the colon and increasing the water content of the stool. This softens the stool and increases its bulk, stimulating bowel movements and facilitating defecation.
Pharmacokinetics
Onset
Typically, bowel movement occurs within 1 to 3 days of starting treatment.
Excretion
Excreted unchanged in the feces.
Half life
Not applicable due to minimal absorption.
Absorption
Minimally absorbed from the gastrointestinal tract (less than 0.2%).
Metabolism
Not metabolized by intestinal flora or in the liver.
Side Effects
Contraindications
- Known hypersensitivity to Polyethylene Glycol
- Bowel obstruction or ileus
- Toxic megacolon or severe ulcerative colitis
- Bowel perforation
- Gastric retention
Drug Interactions
Other Oral Medications
May potentially decrease the absorption of other orally administered drugs if taken simultaneously. It is advisable to separate the administration by at least 2 hours.
Storage
Store at controlled room temperature (20-25°C or 68-77°F). Keep the container tightly closed and protect from moisture. Do not store in the bathroom.
Overdose
Symptoms of overdose include severe diarrhea, abdominal cramps, and electrolyte imbalance. Treatment is symptomatic and supportive, including correction of fluid and electrolyte disturbances.
Pregnancy & Lactation
Generally considered safe for use during pregnancy and lactation due to minimal systemic absorption. However, consult a healthcare professional before use.
Side Effects
Contraindications
- Known hypersensitivity to Polyethylene Glycol
- Bowel obstruction or ileus
- Toxic megacolon or severe ulcerative colitis
- Bowel perforation
- Gastric retention
Drug Interactions
Other Oral Medications
May potentially decrease the absorption of other orally administered drugs if taken simultaneously. It is advisable to separate the administration by at least 2 hours.
Storage
Store at controlled room temperature (20-25°C or 68-77°F). Keep the container tightly closed and protect from moisture. Do not store in the bathroom.
Overdose
Symptoms of overdose include severe diarrhea, abdominal cramps, and electrolyte imbalance. Treatment is symptomatic and supportive, including correction of fluid and electrolyte disturbances.
Pregnancy & Lactation
Generally considered safe for use during pregnancy and lactation due to minimal systemic absorption. However, consult a healthcare professional before use.
Frequently Asked Questions
Common questions about this medicine
Pack Sizes
Shelf Life
Typically 2 to 3 years from the date of manufacture, consult product label for exact expiry.
Availability
Pharmacies, supermarkets
Approval Status
Approved (Generally OTC)
Patent Status
Generic
WHO Essential Medicine
YesClinical Trials
Extensive clinical trials have demonstrated the efficacy and safety of Polyethylene Glycol 3350 for the treatment of various forms of constipation in adults and children.
Lab Monitoring
- Routine lab monitoring is not typically required.
- For prolonged or high-dose use, especially in patients at risk of electrolyte disturbances, periodic monitoring of serum electrolytes may be advisable.
Doctor Notes
- Emphasize proper patient education regarding adequate hydration and duration of use.
- Consider underlying causes of constipation, especially in chronic cases, before initiating treatment.
- Monitor for electrolyte disturbances in patients with pre-existing conditions or on concomitant medications that affect electrolytes.
Patient Guidelines
- Read the patient information leaflet carefully before use.
- Ensure adequate fluid intake while using this medicine.
- Do not use for more than 7 days without consulting a doctor.
- If constipation persists or worsens, seek medical advice.
Missed Dose Advice
If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and resume your regular dosing schedule. Do not double the dose.
Driving Precautions
e-lax-335-gm-oral-solution is not known to affect the ability to drive or operate machinery.
Lifestyle Advice
- Maintain a high-fiber diet.
- Engage in regular physical activity.
- Ensure adequate daily fluid intake.
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Global Brand Names
International brand names for this medicine. Click a brand to search for detailed information.