Ecoren
Generic Name
Econazole Nitrate
Manufacturer
Renata Limited
Country
Bangladesh
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Price Details
Current market pricing information
| Variant | Unit Price | Strip Price |
|---|---|---|
| ecoren 1 cream | ৳ 30.20 | N/A |
Description
Overview of the medicine
Ecoren 1% Cream contains Econazole Nitrate, an antifungal agent used to treat various fungal skin infections such as athlete's foot, jock itch, ringworm, candidiasis, and tinea versicolor.
Uses & Indications
Dosage
Adults
Apply a thin layer of Ecoren 1% Cream to the affected skin area once or twice daily. Gently massage until it disappears. Continue treatment for at least 2 weeks after symptoms disappear to prevent recurrence.
Elderly
No special dosage adjustment is required for elderly patients.
Renal_impairment
Not applicable for topical use as systemic absorption is minimal.
How to Take
Ecoren 1% Cream is for topical use only. Cleanse the affected area before application. Apply a thin layer to the affected skin and surrounding area.
Mechanism of Action
Econazole Nitrate works by inhibiting the biosynthesis of ergosterol, a vital component of fungal cell membranes. This disruption leads to increased cell membrane permeability, leakage of essential intracellular components, and ultimately, fungal cell death.
Pharmacokinetics
Onset
Symptom improvement typically begins within a few days of treatment.
Excretion
Mainly excreted in urine and feces, primarily as metabolites.
Half life
Not clinically significant for topical application due to minimal systemic absorption.
Absorption
Systemic absorption following topical application is minimal (less than 10%), with peak plasma concentrations occurring 1-2 days after application.
Metabolism
Metabolized in the liver to inactive metabolites.
Side Effects
Contraindications
- Hypersensitivity to Econazole Nitrate or any other ingredient of the cream.
Drug Interactions
Warfarin
Topical econazole may potentiate the effect of oral anticoagulants like warfarin, leading to an increased risk of bleeding, although systemic absorption is low. Monitor INR carefully.
Other topical agents
Avoid applying other topical preparations to the same area simultaneously without consulting a doctor, as interactions are possible.
Storage
Store below 30°C. Protect from light and moisture. Keep out of reach of children.
Overdose
Overdose is unlikely with topical application due to minimal systemic absorption. If accidentally ingested, symptomatic and supportive measures should be taken.
Pregnancy & Lactation
Use during pregnancy or lactation should only be considered if the potential benefit outweighs the potential risk to the fetus or infant. Consult your doctor before use. Minimal systemic absorption suggests low risk.
Frequently Asked Questions
Common questions about this medicine
Pack Sizes
Shelf Life
Usually 2-3 years from manufacturing date, refer to packaging for exact expiry.
Availability
Pharmacies, drugstores
Approval Status
Approved by DGDA
Patent Status
Off-patent
Clinical Trials
Econazole Nitrate has been extensively studied in numerous clinical trials demonstrating its efficacy and safety for topical fungal infections. It is a well-established and widely used antifungal.
Lab Monitoring
- No routine laboratory monitoring is typically required for topical Econazole Nitrate.
Doctor Notes
- Advise patients on appropriate hygiene measures to prevent recurrence of fungal infections.
- Emphasize the importance of completing the full course of treatment even if symptoms improve.
- Instruct patients to avoid occlusive dressings unless specifically advised, as this can increase moisture and worsen fungal growth.
Patient Guidelines
- Wash hands thoroughly before and after applying the cream.
- Avoid contact with eyes, nose, mouth, and other mucous membranes. If contact occurs, rinse thoroughly with water.
- Do not cover the treated area with an occlusive dressing unless advised by your doctor.
- Complete the full course of treatment as prescribed, even if symptoms improve earlier, to prevent recurrence.
Missed Dose Advice
If you miss a dose, apply it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not apply a double dose.
Driving Precautions
Ecoren 1% Cream has no known effect on the ability to drive or operate machinery.
Lifestyle Advice
- Keep the affected area clean and dry.
- Wear loose-fitting, breathable clothing, especially for fungal infections in skin folds.
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Global Brand Names
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