Eggcal-D
Generic Name
Calcium Carbonate + Vitamin D3 (Cholecalciferol)
Manufacturer
Renata Limited
Country
Bangladesh
Loading images...
Price Details
Current market pricing information
| Variant | Unit Price | Strip Price |
|---|---|---|
| eggcal d 500 mg tablet | ৳ 10.00 | ৳ 100.00 |
Description
Overview of the medicine
Calcium Carbonate with Vitamin D3 is a dietary supplement used to prevent or treat calcium and vitamin D deficiencies, crucial for bone health and overall physiological functions.
Uses & Indications
Dosage
Adults
Usually 1-2 tablets daily, or as directed by the physician. Dosage may vary based on individual calcium and vitamin D requirements.
Elderly
Same as adults, but caution should be exercised and calcium levels monitored, especially in presence of renal impairment.
Renal_impairment
Use with caution. Dosage may need adjustment based on renal function and serum calcium/phosphate levels. Not recommended in severe renal impairment.
How to Take
Oral administration. Tablets can be taken with or without food, but taking with meals may enhance calcium absorption. Do not chew or crush the tablet; swallow whole with water.
Mechanism of Action
Calcium is essential for bone formation and maintenance, nerve transmission, muscle contraction, and many cellular functions. Vitamin D3 helps in the absorption of calcium from the gut and its deposition in bones, and plays a role in regulating calcium and phosphate homeostasis.
Pharmacokinetics
Onset
Therapeutic effects on bone density are long-term, not immediate, and require consistent supplementation over time.
Excretion
Calcium is excreted primarily via kidneys (urine) and feces. Vitamin D metabolites are primarily excreted in bile and feces, with some renal excretion.
Half life
Calcium has no true half-life as it's an essential mineral. Vitamin D3 has a half-life of about 15-20 hours; its active metabolite, calcitriol, has a half-life of 3-6 hours.
Absorption
Calcium is absorbed primarily in the small intestine via active transport and passive diffusion. Vitamin D3 is absorbed from the small intestine, primarily in the jejunum, and is dependent on bile salts.
Metabolism
Calcium is not metabolized in the traditional sense. Vitamin D3 is hydroxylated in the liver to 25-hydroxyvitamin D [25(OH)D] and then in the kidney to 1,25-dihydroxyvitamin D [1,25(OH)2D] (calcitriol).
Side Effects
Contraindications
- Hypersensitivity to calcium, vitamin D, or any components of the tablet
- Hypercalcemia (high calcium levels in blood)
- Hypercalciuria (high calcium levels in urine)
- Severe renal impairment or renal failure
- History of renal calculi (kidney stones)
- Primary hyperparathyroidism
Drug Interactions
Levothyroxine
Calcium can impair the absorption of levothyroxine. Take calcium supplements at least 4 hours apart from levothyroxine.
Bisphosphonates
Calcium can interfere with the absorption of bisphosphonates. Take calcium at least 30 minutes to 2 hours after bisphosphonates.
Corticosteroids
Can decrease calcium absorption.
Thiazide diuretics
May reduce calcium excretion, increasing the risk of hypercalcemia.
Cardiac glycosides (e.g., Digoxin)
Hypercalcemia can potentiate the effects of cardiac glycosides, increasing the risk of arrhythmias.
Tetracyclines & Fluoroquinolones (antibiotics)
Calcium can chelate these antibiotics, reducing their absorption. Take calcium supplements at least 2-3 hours before or 4-6 hours after these antibiotics.
Storage
Store below 30°C in a cool, dry place, protected from light and moisture. Keep out of reach of children.
Overdose
Symptoms of overdose include nausea, vomiting, constipation, extreme thirst, polyuria (frequent urination), muscle weakness, fatigue, confusion, and in severe cases, cardiac arrhythmias and coma. Management involves immediate discontinuation of the supplement, ensuring adequate hydration (oral or intravenous fluids), and symptomatic treatment. In severe cases of hypercalcemia, diuretics and corticosteroids may be used.
Pregnancy & Lactation
Generally considered safe and often recommended as a supplement during pregnancy and lactation to meet increased demands for calcium and vitamin D, but should be taken under medical supervision and not exceeding recommended daily allowances.
Side Effects
Contraindications
- Hypersensitivity to calcium, vitamin D, or any components of the tablet
- Hypercalcemia (high calcium levels in blood)
- Hypercalciuria (high calcium levels in urine)
- Severe renal impairment or renal failure
- History of renal calculi (kidney stones)
- Primary hyperparathyroidism
Drug Interactions
Levothyroxine
Calcium can impair the absorption of levothyroxine. Take calcium supplements at least 4 hours apart from levothyroxine.
Bisphosphonates
Calcium can interfere with the absorption of bisphosphonates. Take calcium at least 30 minutes to 2 hours after bisphosphonates.
Corticosteroids
Can decrease calcium absorption.
Thiazide diuretics
May reduce calcium excretion, increasing the risk of hypercalcemia.
Cardiac glycosides (e.g., Digoxin)
Hypercalcemia can potentiate the effects of cardiac glycosides, increasing the risk of arrhythmias.
Tetracyclines & Fluoroquinolones (antibiotics)
Calcium can chelate these antibiotics, reducing their absorption. Take calcium supplements at least 2-3 hours before or 4-6 hours after these antibiotics.
Storage
Store below 30°C in a cool, dry place, protected from light and moisture. Keep out of reach of children.
Overdose
Symptoms of overdose include nausea, vomiting, constipation, extreme thirst, polyuria (frequent urination), muscle weakness, fatigue, confusion, and in severe cases, cardiac arrhythmias and coma. Management involves immediate discontinuation of the supplement, ensuring adequate hydration (oral or intravenous fluids), and symptomatic treatment. In severe cases of hypercalcemia, diuretics and corticosteroids may be used.
Pregnancy & Lactation
Generally considered safe and often recommended as a supplement during pregnancy and lactation to meet increased demands for calcium and vitamin D, but should be taken under medical supervision and not exceeding recommended daily allowances.
Frequently Asked Questions
Common questions about this medicine
Pack Sizes
Shelf Life
36 months from manufacturing date (typical)
Availability
Pharmacies, Drug stores
Approval Status
Approved by DGDA (Bangladesh)
Patent Status
Generic/Off-patent
Clinical Trials
The efficacy and safety of Calcium Carbonate and Vitamin D3 combination for bone health and deficiency states are well-established through numerous clinical trials and studies. Specific trials for Eggcal-D as a brand are not typically reported publicly for generic supplements.
Lab Monitoring
- Serum calcium levels (especially in patients with renal impairment or on long-term therapy)
- Serum vitamin D levels (25-hydroxyvitamin D) to assess deficiency or sufficiency
- Renal function tests (creatinine, GFR) in patients with kidney issues
- Urine calcium excretion (if hypercalciuria is suspected or in patients with a history of kidney stones)
Doctor Notes
- Emphasize the importance of adequate fluid intake to minimize the risk of kidney stones.
- Advise patients on potential drug-drug and drug-food interactions, especially with antibiotics, thyroid hormones, and bisphosphonates.
- Monitor serum calcium and vitamin D levels periodically in at-risk patients or those on prolonged therapy.
Patient Guidelines
- Take the medicine exactly as prescribed by your doctor or as indicated on the label.
- Do not exceed the recommended dose without consulting a healthcare professional.
- Inform your doctor about all other medications, supplements, and herbal products you are taking.
- Maintain a balanced diet rich in calcium and vitamin D, and ensure adequate fluid intake.
Missed Dose Advice
If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and resume your regular dosing schedule. Do not double dose to make up for a missed one.
Driving Precautions
Eggcal-D is not known to affect the ability to drive or operate machinery. No specific precautions are required.
Lifestyle Advice
- Engage in regular weight-bearing exercise (e.g., walking, jogging) to support bone health.
- Ensure adequate sun exposure (10-15 minutes, 2-3 times a week, depending on skin type and location) for natural vitamin D synthesis, while also protecting against excessive UV radiation.
- Avoid smoking and excessive alcohol consumption, as these can negatively impact bone density and calcium absorption.
Alternative Medicines in Bangladesh
Similar medicines available in the market
Global Brand Names
International brand names for this medicine. Click a brand to search for detailed information.