Oral administration. Shake the suspension well before each use. Can be taken with or without food, but taking on an empty stomach (1 hour before or 2 hours after meals) may improve absorption for some formulations. Complete the full course of treatment.

Erythromycin inhibits bacterial protein synthesis by binding reversibly to the 50S ribosomal subunit of susceptible microorganisms, thereby blocking translocation of peptidyl tRNA.

• •Hypersensitivity to erythromycin or any other macrolide antibiotic.
• •Co-administration with terfenadine, astemizole, cisapride, pimozide, or ergot alkaloids due to risk of serious cardiac arrhythmias (QT prolongation).
• •Patients with pre-existing liver disease or cholestatic jaundice history related to erythromycin.

Store the dry powder below 30°C, protected from light and moisture. Once reconstituted, store the suspension in a refrigerator (2-8°C) and discard any unused portion after the specified period.

Symptoms of overdose may include severe nausea, vomiting, abdominal pain, and diarrhea. Management involves gastric lavage, activated charcoal, and supportive care. Monitor cardiac function (ECG).

Pregnancy Category B. Generally considered safe during pregnancy when indicated. Compatible with breastfeeding; passes into breast milk in small amounts, but typically not harmful to the infant.