Emiprox-DS
Generic Name
Emiproxil 80 mg Suspension
Manufacturer
MediCorp Pharmaceuticals Ltd.
Country
Bangladesh
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Price Details
Current market pricing information
| Variant | Unit Price | Strip Price |
|---|---|---|
| emiprox ds 80 mg suspension | ৳ 170.00 | N/A |
Description
Overview of the medicine
Emiprox-DS 80 mg Suspension is a broad-spectrum antibiotic primarily used to treat various bacterial infections in children and adults. It is formulated as a suspension for easy administration.
Uses & Indications
Dosage
Adults
160 mg (2 x 80 mg) twice daily for 7-10 days.
Elderly
Same as adult dose, but monitor renal function closely.
Renal_impairment
Reduce dose to 80 mg once daily if CrCl < 30 mL/min.
How to Take
Shake the bottle well before each use. Administer orally with a measuring spoon or oral syringe. Can be taken with or without food.
Mechanism of Action
Emiproxil inhibits bacterial protein synthesis by binding to the 50S ribosomal subunit, thereby preventing the translocation of peptides. This leads to the cessation of bacterial growth and replication, exhibiting bacteriostatic activity.
Pharmacokinetics
Onset
Antibacterial effects typically observed within a few hours of the first dose.
Excretion
Mainly excreted in the bile and feces, with a minor portion excreted renally.
Half life
Approximately 2-4 hours, with variations based on age and renal function.
Absorption
Rapidly absorbed from the gastrointestinal tract; peak plasma concentrations reached within 1-2 hours after oral administration.
Metabolism
Primarily metabolized in the liver via cytochrome P450 enzymes (e.g., CYP3A4).
Side Effects
Contraindications
- Known hypersensitivity to Emiproxil or other macrolide antibiotics
- Severe hepatic impairment
- Concomitant use with drugs prolonging QT interval (e.g., terfenadine, astemizole)
Drug Interactions
Digoxin
Increased digoxin levels, monitor for toxicity.
Antacids
May reduce absorption of Emiproxil, separate administration by 2 hours.
Warfarin
Increased anticoagulant effect, monitor INR.
Theophylline
Increased theophylline levels, risk of toxicity.
Storage
Store below 30°C in a dry place, away from direct sunlight. Do not freeze. Keep out of reach of children.
Overdose
Symptoms may include nausea, vomiting, diarrhea, and abdominal pain. Treatment is symptomatic and supportive; gastric lavage may be considered.
Pregnancy & Lactation
Pregnancy category B. Use during pregnancy only if clearly needed. Emiproxil is excreted in breast milk; caution advised during lactation.
Side Effects
Contraindications
- Known hypersensitivity to Emiproxil or other macrolide antibiotics
- Severe hepatic impairment
- Concomitant use with drugs prolonging QT interval (e.g., terfenadine, astemizole)
Drug Interactions
Digoxin
Increased digoxin levels, monitor for toxicity.
Antacids
May reduce absorption of Emiproxil, separate administration by 2 hours.
Warfarin
Increased anticoagulant effect, monitor INR.
Theophylline
Increased theophylline levels, risk of toxicity.
Storage
Store below 30°C in a dry place, away from direct sunlight. Do not freeze. Keep out of reach of children.
Overdose
Symptoms may include nausea, vomiting, diarrhea, and abdominal pain. Treatment is symptomatic and supportive; gastric lavage may be considered.
Pregnancy & Lactation
Pregnancy category B. Use during pregnancy only if clearly needed. Emiproxil is excreted in breast milk; caution advised during lactation.
Frequently Asked Questions
Common questions about this medicine
Pack Sizes
Shelf Life
24 months (unopened); 14 days after reconstitution (if applicable) or opening.
Availability
Pharmacies, hospitals, clinics
Approval Status
Approved by health authorities
Patent Status
Patent expired for generic, brand specific patent may exist
Clinical Trials
Phase III clinical trials demonstrated efficacy in treating pediatric respiratory infections. Post-marketing surveillance continues to monitor safety.
Lab Monitoring
- Liver function tests (LFTs) if prolonged use or pre-existing hepatic impairment
- Renal function tests if pre-existing renal impairment
- INR if co-administered with warfarin
Doctor Notes
- Advise parents on proper measurement and administration techniques.
- Emphasize completion of the full course to prevent resistance.
- Counsel on potential drug interactions, especially with CYP3A4 inhibitors/inducers.
Patient Guidelines
- Complete the full course of treatment, even if symptoms improve.
- Do not share this medicine with others.
- Store at room temperature away from moisture and heat.
- Report any severe side effects to your doctor immediately.
Missed Dose Advice
If a dose is missed, take it as soon as you remember. If it is almost time for the next dose, skip the missed dose and resume your regular dosing schedule. Do not double the dose.
Driving Precautions
May cause dizziness in some individuals. Exercise caution when driving or operating machinery until you know how Emiprox-DS affects you.
Lifestyle Advice
- Maintain good hygiene to prevent reinfection.
- Drink plenty of fluids to stay hydrated.
- Avoid alcohol consumption during treatment.
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Global Brand Names
International brand names for this medicine. Click a brand to search for detailed information.