Enerplat
Generic Name
Eperisone Hydrochloride
Manufacturer
Square Pharmaceuticals Ltd.
Country
Bangladesh
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Price Details
Current market pricing information
| Variant | Unit Price | Strip Price |
|---|---|---|
| enerplat 50 mg tablet | ৳ 900.00 | ৳ 6,300.00 |
Description
Overview of the medicine
Enerplat 50 mg Tablet contains Eperisone Hydrochloride, a centrally acting muscle relaxant used to improve muscle tone, relieve muscle spasms, and reduce pain.
Uses & Indications
Dosage
Adults
Typically 50 mg three times daily, after meals. Dosage may be adjusted based on symptoms and age.
Elderly
Lower doses may be considered, with careful monitoring due to potential increased sensitivity.
Renal_impairment
Use with caution. Dosage adjustment may be required.
How to Take
Take orally with water, after meals. Do not chew or crush the tablet.
Mechanism of Action
Eperisone acts by inhibiting the alpha-motor neurons in the spinal cord, leading to the relaxation of skeletal muscles. It also has vasodilatory properties, improving blood circulation and reducing pain.
Pharmacokinetics
Onset
Onset of action typically within 1 hour.
Excretion
Mainly excreted via the kidneys as metabolites.
Half life
Plasma half-life is approximately 1.5 to 2 hours.
Absorption
Rapidly absorbed after oral administration. Peak plasma concentration reached within 1.5 to 2 hours.
Metabolism
Extensively metabolized in the liver, primarily by CYP450 enzymes.
Side Effects
Contraindications
- Hypersensitivity to Eperisone or any component of the tablet
- Lactation
Drug Interactions
Tolperisone
Concurrent use may lead to increased side effects.
Storage
Store in a cool, dry place, below 30°C. Protect from light and moisture. Keep out of reach of children.
Overdose
Symptoms of overdose may include nausea, vomiting, dizziness, drowsiness, and hypotension. Treatment is symptomatic and supportive. Gastric lavage may be considered.
Pregnancy & Lactation
Pregnancy Category C. Should be used during pregnancy only if the potential benefit justifies the potential risk to the fetus. Contraindicated during lactation.
Side Effects
Contraindications
- Hypersensitivity to Eperisone or any component of the tablet
- Lactation
Drug Interactions
Tolperisone
Concurrent use may lead to increased side effects.
Storage
Store in a cool, dry place, below 30°C. Protect from light and moisture. Keep out of reach of children.
Overdose
Symptoms of overdose may include nausea, vomiting, dizziness, drowsiness, and hypotension. Treatment is symptomatic and supportive. Gastric lavage may be considered.
Pregnancy & Lactation
Pregnancy Category C. Should be used during pregnancy only if the potential benefit justifies the potential risk to the fetus. Contraindicated during lactation.
Frequently Asked Questions
Common questions about this medicine
Pack Sizes
Shelf Life
36 months from manufacturing date.
Availability
Available in pharmacies nationwide
Approval Status
Approved (local regulatory bodies like DGDA)
Patent Status
Off-patent
Clinical Trials
Numerous clinical trials have demonstrated Eperisone's efficacy and safety in treating various musculoskeletal conditions and spasticity.
Lab Monitoring
- Liver function tests (LFTs) if long-term use or hepatic impairment is suspected.
- Renal function tests (RFTs) if renal impairment is suspected.
Doctor Notes
- Advise patients to take with food to minimize GI upset.
- Monitor for signs of hypersensitivity, especially skin reactions.
- Caution in patients with hepatic or renal impairment.
Patient Guidelines
- Take medicine exactly as prescribed by your doctor.
- Do not stop taking the medicine abruptly without consulting your doctor.
- Avoid alcohol while on this medication.
Missed Dose Advice
If you miss a dose, take it as soon as you remember. If it's nearly time for your next dose, skip the missed dose and continue your regular dosing schedule. Do not double the dose.
Driving Precautions
May cause dizziness or drowsiness. Avoid driving or operating heavy machinery until you know how this medicine affects you.
Lifestyle Advice
- Engage in light exercises as advised by a physiotherapist.
- Maintain a healthy posture.
- Avoid sudden movements that aggravate muscle spasms.
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Global Brand Names
International brand names for this medicine. Click a brand to search for detailed information.