Enocef

Cefazolin can be administered by deep intramuscular injection or by intravenous injection/infusion. For intravenous administration, the powder should be reconstituted with an appropriate diluent (e.g., Sterile Water for Injection) and further diluted for infusion if necessary.

Cefazolin is a bactericidal antibiotic that acts by inhibiting bacterial cell wall synthesis. It binds to penicillin-binding proteins (PBPs) located inside the bacterial cell wall, which prevents the cross-linking of peptidoglycan chains, leading to cell lysis and bacterial death.

• Hypersensitivity to cefazolin or other cephalosporins.
• History of severe hypersensitivity (e.g., anaphylaxis) to any type of beta-lactam antibiotic (e.g., penicillins).

Store below 30°C in a dry place, away from light. Do not freeze. Keep out of reach of children. Reconstituted solutions should be used immediately or stored as per specific instructions.

Symptoms of overdose may include nausea, vomiting, epigastric distress, diarrhea, and rarely, seizures (especially in patients with renal impairment). Management is primarily supportive; hemodialysis may be useful in removing cefazolin from the blood in cases of severe overdose with renal failure.

Pregnancy Category B. Studies in animals have shown no evidence of harm to the fetus, but there are no adequate and well-controlled studies in pregnant women. Use during pregnancy only if clearly needed. Cefazolin is excreted in small amounts in breast milk; caution should be exercised when administering to a nursing mother.

• Hypersensitivity to cefazolin or other cephalosporins.
• History of severe hypersensitivity (e.g., anaphylaxis) to any type of beta-lactam antibiotic (e.g., penicillins).

Store below 30°C in a dry place, away from light. Do not freeze. Keep out of reach of children. Reconstituted solutions should be used immediately or stored as per specific instructions.

Symptoms of overdose may include nausea, vomiting, epigastric distress, diarrhea, and rarely, seizures (especially in patients with renal impairment). Management is primarily supportive; hemodialysis may be useful in removing cefazolin from the blood in cases of severe overdose with renal failure.

Pregnancy Category B. Studies in animals have shown no evidence of harm to the fetus, but there are no adequate and well-controlled studies in pregnant women. Use during pregnancy only if clearly needed. Cefazolin is excreted in small amounts in breast milk; caution should be exercised when administering to a nursing mother.