Erythromycin
Generic Name
Erythromycin 250 mg tablet
Manufacturer
Various Pharmaceutical Companies
Country
Global / Various
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Price Details
Current market pricing information
| Variant | Unit Price | Strip Price |
|---|---|---|
| ery 250 mg tablet | ৳ 5.17 | ৳ 51.70 |
Description
Overview of the medicine
Erythromycin is a macrolide antibiotic used to treat a wide variety of bacterial infections. It works by stopping the growth of bacteria.
Uses & Indications
Dosage
Adults
250-500 mg every 6 hours, or 500 mg every 12 hours, depending on the severity of infection.
Elderly
Similar to adult dosage, but with caution due to potential renal/hepatic impairment.
Renal_impairment
No dosage adjustment usually needed for mild-moderate impairment; caution in severe impairment.
How to Take
Oral administration. May be taken with or without food, but food may reduce GI upset.
Mechanism of Action
Binds to the 50S ribosomal subunit of susceptible microorganisms, inhibiting protein synthesis by blocking the polypeptide exit tunnel.
Pharmacokinetics
Onset
1-4 hours
Excretion
Primarily bile/feces; small amount via urine
Half life
1.5-2 hours (in adults with normal renal function)
Absorption
Variably absorbed from the GI tract; improved with enteric-coated forms or esters.
Metabolism
Hepatic, via CYP3A4
Side Effects
Contraindications
- •Hypersensitivity to erythromycin or other macrolides
- •Concurrent use with astemizole, terfenadine, cisapride, pimozide, or colchicine
Drug Interactions
Digoxin
Increased digoxin levels.
Warfarin
Increased anticoagulant effect.
Statins (e.g., Simvastatin)
Increased risk of myopathy/rhabdomyolysis.
Storage
Store at room temperature (20-25°C), away from moisture and light. Keep out of reach of children.
Overdose
Symptoms include nausea, vomiting, abdominal cramps, diarrhea, and hearing loss (reversible). Management is supportive and symptomatic.
Pregnancy & Lactation
Pregnancy Category B. Generally considered safe during pregnancy. Excreted into breast milk, but generally considered compatible with breastfeeding.
Frequently Asked Questions
Common questions about this medicine
Pack Sizes
Shelf Life
2-3 years from manufacturing date
Availability
Pharmacies, Hospitals
Approval Status
Approved by major regulatory bodies (e.g., FDA, DGDA)
Patent Status
Generic available (patent expired)
WHO Essential Medicine
YesAlternative Medicines in Bangladesh
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Global Brand Names
International brand names for this medicine
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