Ethivit-B
Generic Name
Vitamin B Complex (e.g., Thiamine, Riboflavin, Pyridoxine HCl 5mg, Nicotinamide, Calcium Pantothenate)
Manufacturer
Acme Laboratories Ltd.
Country
Bangladesh
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Price Details
Current market pricing information
| Variant | Unit Price | Strip Price |
|---|---|---|
| ethivit b 5 mg tablet | ৳ 0.51 | N/A |
Description
Overview of the medicine
Ethivit-B 5 mg Tablet is a vitamin B complex preparation containing essential B vitamins crucial for various metabolic processes, neurological functions, and overall health. The '5 mg' typically refers to the Pyridoxine (Vitamin B6) content.
Uses & Indications
Dosage
Adults
Usually 1-2 tablets daily, or as directed by a physician. The dosage may vary based on the severity of deficiency and individual needs.
Elderly
No specific dosage adjustment is typically required for elderly patients, but monitoring for potential malabsorption or renal function is advisable.
Renal_impairment
Generally, no specific dosage adjustment is needed for mild to moderate renal impairment. For severe impairment, caution is advised, and a physician should be consulted.
How to Take
Ethivit-B 5 mg Tablet is for oral administration. It can be taken with or without food. Taking it with food may help reduce gastrointestinal upset.
Mechanism of Action
The B vitamins in Ethivit-B act as coenzymes in various metabolic pathways, including carbohydrate, protein, and fat metabolism. They are vital for energy production, DNA synthesis, red blood cell formation, and nervous system function.
Pharmacokinetics
Onset
Therapeutic effects may be observed within hours to days, depending on the specific vitamin deficiency and individual response.
Excretion
Excreted renally, primarily as metabolites or unchanged vitamins, especially excess amounts.
Half life
Varies significantly among individual B vitamins (e.g., Thiamine elimination half-life is around 9-18 days, Pyridoxine half-life is about 15-20 days). Water-soluble vitamins are generally not stored in large amounts.
Absorption
B vitamins are generally well absorbed from the gastrointestinal tract, primarily in the small intestine.
Metabolism
Primarily hepatic, where they are converted into their active coenzyme forms.
Side Effects
Contraindications
- Hypersensitivity to any of the active ingredients or excipients in the tablet.
Drug Interactions
Alcohol
Chronic alcohol consumption can impair the absorption and utilization of several B vitamins, including thiamine and folic acid.
Antacids
May impair the absorption of certain B vitamins, particularly Vitamin B12.
Levodopa
Pyridoxine (Vitamin B6) can reduce the effectiveness of levodopa (used in Parkinson's disease) by enhancing its peripheral metabolism. This interaction is usually significant with higher doses of pyridoxine.
Isoniazid, Penicillamine, Oral Contraceptives
These medications can increase the requirement for pyridoxine and may lead to its deficiency.
Storage
Store in a cool, dry place, below 30°C. Protect from light and moisture.
Overdose
Overdose with water-soluble vitamins like those in Ethivit-B is rare, as excess amounts are typically excreted renally. However, very high doses of Pyridoxine (Vitamin B6) over extended periods can lead to peripheral neuropathy. Symptomatic and supportive measures should be taken in case of an accidental overdose, and medical attention should be sought.
Pregnancy & Lactation
B vitamins are essential during pregnancy and lactation for both maternal and fetal/infant health. Ethivit-B is generally considered safe when taken at recommended doses. However, consultation with a healthcare professional is advisable before use during these periods.
Side Effects
Contraindications
- Hypersensitivity to any of the active ingredients or excipients in the tablet.
Drug Interactions
Alcohol
Chronic alcohol consumption can impair the absorption and utilization of several B vitamins, including thiamine and folic acid.
Antacids
May impair the absorption of certain B vitamins, particularly Vitamin B12.
Levodopa
Pyridoxine (Vitamin B6) can reduce the effectiveness of levodopa (used in Parkinson's disease) by enhancing its peripheral metabolism. This interaction is usually significant with higher doses of pyridoxine.
Isoniazid, Penicillamine, Oral Contraceptives
These medications can increase the requirement for pyridoxine and may lead to its deficiency.
Storage
Store in a cool, dry place, below 30°C. Protect from light and moisture.
Overdose
Overdose with water-soluble vitamins like those in Ethivit-B is rare, as excess amounts are typically excreted renally. However, very high doses of Pyridoxine (Vitamin B6) over extended periods can lead to peripheral neuropathy. Symptomatic and supportive measures should be taken in case of an accidental overdose, and medical attention should be sought.
Pregnancy & Lactation
B vitamins are essential during pregnancy and lactation for both maternal and fetal/infant health. Ethivit-B is generally considered safe when taken at recommended doses. However, consultation with a healthcare professional is advisable before use during these periods.
Frequently Asked Questions
Common questions about this medicine
Pack Sizes
Shelf Life
2-3 years from manufacturing date
Availability
Pharmacies, drugstores
Approval Status
Approved (DGDA, Bangladesh)
Patent Status
Patent expired
Clinical Trials
As an established vitamin preparation, extensive new clinical trials are generally not required for Ethivit-B. Its efficacy and safety are well-documented for B vitamins.
Lab Monitoring
- Routine laboratory monitoring is generally not required. However, specific vitamin B levels (e.g., Vitamin B12) may be monitored in cases of suspected deficiency or specific medical conditions.
Doctor Notes
- Advise patients on the importance of a balanced diet alongside supplementation.
- Caution against exceeding recommended doses, especially with Pyridoxine (B6), to avoid potential neuropathy.
- Consider underlying causes of vitamin B deficiency and address them if necessary.
Patient Guidelines
- Take the medicine exactly as prescribed or as directed on the label.
- Do not exceed the recommended dose.
- Keep out of reach of children.
- Store in a cool, dry place away from direct light and moisture.
Missed Dose Advice
If a dose is missed, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and resume your regular dosing schedule. Do not take a double dose to make up for a missed one.
Driving Precautions
Ethivit-B 5 mg Tablet is generally not expected to impair the ability to drive or operate machinery.
Lifestyle Advice
- Maintain a balanced diet rich in fruits, vegetables, and whole grains to ensure adequate intake of essential nutrients.
- Adopt a healthy lifestyle with regular exercise and sufficient rest.
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