OcuVisc
Generic Name
Sodium Hyaluronate Viscoelastic Solution
Manufacturer
Vision Pharmaceuticals Ltd.
Country
Bangladesh
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Price Details
Current market pricing information
| Variant | Unit Price | Strip Price |
|---|---|---|
| eye gel 2 viscoelastic solution | ৳ 120.45 | N/A |
Description
Overview of the medicine
A sterile, non-pyrogenic, transparent, viscoelastic solution containing sodium hyaluronate, designed to protect ocular tissues and maintain space during anterior segment ophthalmic surgeries such as cataract extraction and intraocular lens implantation. It aids in creating and maintaining space, pushing back the vitreous face, and protecting the endothelium and other intraocular tissues from surgical trauma.
Uses & Indications
Dosage
Adults
Administer intraocularly as required by the surgeon to facilitate surgical procedures and protect ocular tissues. Typically 0.5 mL to 1.0 mL per procedure.
Elderly
No specific dosage adjustment required for elderly patients.
Renal_impairment
Not applicable as systemic absorption is minimal.
How to Take
Administered intraocularly by a qualified ophthalmologist using a sterile syringe and cannula during ophthalmic surgical procedures. Avoid overfilling the eye.
Mechanism of Action
Sodium hyaluronate is a high molecular weight polysaccharide that acts as a viscoelastic agent. When introduced into the anterior chamber of the eye, it coats and protects intraocular tissues, provides a barrier against surgical instruments, and helps maintain the depth of the anterior chamber, facilitating surgical maneuvers. Its viscoelastic properties allow it to absorb and dissipate energy, reducing mechanical trauma to delicate ocular structures.
Pharmacokinetics
Onset
Immediate upon instillation.
Excretion
Mainly via trabecular outflow pathway and enzymatic degradation products are absorbed and excreted systemically.
Half life
Approximately 2-3 days in the human eye, depending on molecular weight and concentration.
Absorption
Intraocularly administered; it is slowly eliminated from the anterior chamber via the trabecular meshwork and potentially by enzymatic degradation.
Metabolism
Gradual enzymatic degradation by hyaluronidases in the eye.
Side Effects
Contraindications
- Hypersensitivity to sodium hyaluronate or any component of the formulation.
- Infections in the eye (relative contraindication, should be treated first).
Drug Interactions
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Storage
Store at 2°C to 8°C (36°F to 46°F). Do not freeze. Protect from light. Bring to room temperature before use.
Overdose
Overfilling the anterior chamber may lead to transient postoperative intraocular pressure elevation. Management involves aspiration of excess viscoelastic material and/or medical management of elevated IOP.
Pregnancy & Lactation
Use with caution. Animal reproduction studies have not been conducted. It is unlikely to cause systemic effects due to minimal systemic absorption. Consult a physician.
Side Effects
Contraindications
- Hypersensitivity to sodium hyaluronate or any component of the formulation.
- Infections in the eye (relative contraindication, should be treated first).
Drug Interactions
0
N
1
o
2
n
3
e
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s
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p
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123
.
Storage
Store at 2°C to 8°C (36°F to 46°F). Do not freeze. Protect from light. Bring to room temperature before use.
Overdose
Overfilling the anterior chamber may lead to transient postoperative intraocular pressure elevation. Management involves aspiration of excess viscoelastic material and/or medical management of elevated IOP.
Pregnancy & Lactation
Use with caution. Animal reproduction studies have not been conducted. It is unlikely to cause systemic effects due to minimal systemic absorption. Consult a physician.
Frequently Asked Questions
Common questions about this medicine
Pack Sizes
Shelf Life
Typically 2-3 years from manufacturing date, when stored properly.
Availability
Hospitals, surgical centers, specialized pharmacies
Approval Status
Approved by regulatory bodies (e.g., FDA, DGDA)
Patent Status
Generic available, original patent expired
Clinical Trials
Numerous clinical trials have demonstrated the safety and efficacy of sodium hyaluronate viscoelastic solutions in various ophthalmic surgical procedures, showing reduced endothelial cell loss and improved surgical outcomes compared to non-viscoelastic controls.
Lab Monitoring
- Monitor intraocular pressure post-operatively.
- Regular ophthalmic examination.
Doctor Notes
- Ensure proper removal of residual viscoelastic material at the end of surgery to minimize post-operative IOP spikes.
- Verify product integrity and expiration date before use.
- Store refrigerated; allow to reach room temperature before injection for optimal handling.
Patient Guidelines
- This product is for professional surgical use only.
- Patients should follow all post-operative instructions given by their surgeon.
- Report any unusual pain, redness, or vision changes immediately.
Missed Dose Advice
Not applicable for a single-use surgical agent.
Driving Precautions
Driving is generally not advised immediately after ophthalmic surgery. Follow your surgeon's advice.
Lifestyle Advice
- Avoid rubbing the eye post-surgery.
- Follow all post-operative care instructions.
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