Famogen
Generic Name
Famotidine
Manufacturer
Square Pharmaceuticals Ltd.
Country
Bangladesh
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Price Details
Current market pricing information
| Variant | Unit Price | Strip Price |
|---|---|---|
| famogen 40 mg suspension | ৳ 55.00 | N/A |
Description
Overview of the medicine
Famogen (Famotidine) is an H2-receptor antagonist that reduces the amount of acid the stomach produces. It is used to treat and prevent ulcers in the stomach and intestines, and conditions where the stomach produces too much acid, such as Zollinger-Ellison syndrome.
Uses & Indications
Dosage
Adults
Duodenal ulcer: 40 mg once daily at bedtime or 20 mg twice daily for 4-8 weeks. GERD: 20-40 mg twice daily for up to 12 weeks.
Elderly
Dosage adjustment may be required in elderly patients with reduced renal function.
Renal_impairment
Dosage reduction (e.g., 20 mg once daily) or increased dosing interval if creatinine clearance < 50 mL/min.
How to Take
Oral tablets can be taken with or without food. IV injection is administered slowly over 15-30 minutes.
Mechanism of Action
Famotidine competitively inhibits histamine at the H2-receptors of the gastric parietal cells, leading to a reduction in gastric acid secretion, both basal and stimulated.
Pharmacokinetics
Onset
1 hour (oral)
Excretion
Primarily eliminated by the kidneys (65-70% as unchanged drug).
Half life
2.5-4 hours (increased in renal impairment)
Absorption
Rapidly absorbed after oral administration. Bioavailability: 40-45%.
Metabolism
Partially metabolized in the liver to an inactive sulfoxide metabolite.
Side Effects
Contraindications
- •Hypersensitivity to Famotidine or other H2-receptor antagonists
- •Acute porphyria
Drug Interactions
Aspirin/NSAIDs
Famotidine may reduce their irritant effect on gastric mucosa.
Cefpodoxime/Cefuroxime
Reduced absorption.
Ketoconazole/Itraconazole
Reduced absorption due to increased gastric pH.
Storage
Store below 30°C, protected from light and moisture. Keep out of reach of children.
Overdose
Symptoms include hypotension, tachycardia, vomiting, abdominal pain, and collapse. Management is symptomatic and supportive; gastric lavage may be considered.
Pregnancy & Lactation
Pregnancy category B. Use only if clearly needed. Excreted in breast milk, caution advised.
Frequently Asked Questions
Common questions about this medicine
Pack Sizes
Shelf Life
24-36 months (typically)
Availability
Pharmacies, Hospitals
Approval Status
Approved by regulatory bodies (e.g., FDA, DGDA)
Patent Status
Generic available (patent expired)
WHO Essential Medicine
YesAlternative Medicines in Bangladesh
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Global Brand Names
International brand names for this medicine
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