Fd-120
Generic Name
Fexofenadine Hydrochloride
Manufacturer
MediCorp Pharma
Country
Bangladesh
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Price Details
Current market pricing information
| Variant | Unit Price | Strip Price |
|---|---|---|
| fd 120 120 mg tablet | ৳ 7.00 | ৳ 70.03 |
Description
Overview of the medicine
Fd-120 is an antihistamine containing Fexofenadine Hydrochloride, used to relieve allergy symptoms such as sneezing, runny nose, watery eyes, and itchy throat. It is also used to treat chronic urticaria (hives) in adults and children.
Uses & Indications
Dosage
Adults
120 mg or 180 mg once daily orally.
Elderly
No dose adjustment generally required, but caution in patients with renal impairment.
Renal_impairment
Initial dose of 60 mg once daily. Adjust based on kidney function.
How to Take
Take orally with or without food. Do not take with fruit juices as it may reduce absorption.
Mechanism of Action
Fexofenadine is a selective peripheral H1-blocker. It works by blocking histamine H1 receptors, thereby preventing histamine from binding to these receptors and reducing allergic symptoms. Unlike older antihistamines, it causes less drowsiness because it does not readily cross the blood-brain barrier.
Pharmacokinetics
Onset
Within 1 hour
Excretion
Primarily excreted unchanged in feces (80%) and urine (12%)
Half life
Approximately 11-15 hours
Absorption
Rapidly absorbed after oral administration, peak plasma concentrations reached in 2-3 hours.
Metabolism
Minimal hepatic metabolism, primarily via CYP3A4 pathway (minor)
Side Effects
Contraindications
- Hypersensitivity to fexofenadine or any excipients
- Children under 6 years for allergic rhinitis and under 6 months for urticaria (general guidance, actual age may vary by formulation/country)
Drug Interactions
Erythromycin/Ketoconazole
May increase fexofenadine plasma levels.
Aluminum and Magnesium containing antacids
May decrease fexofenadine absorption if taken concurrently. Separate administration by at least 2 hours.
Storage
Store below 30°C in a dry place, away from light and moisture. Keep out of reach of children.
Overdose
Symptoms of overdose may include dizziness, drowsiness, and dry mouth. Treatment is symptomatic and supportive. Gastric lavage and activated charcoal may be considered.
Pregnancy & Lactation
Pregnancy Category C. Use only if potential benefit justifies potential risk to the fetus. It is unknown if fexofenadine is excreted in human milk; caution should be exercised when administered to a nursing mother.
Side Effects
Contraindications
- Hypersensitivity to fexofenadine or any excipients
- Children under 6 years for allergic rhinitis and under 6 months for urticaria (general guidance, actual age may vary by formulation/country)
Drug Interactions
Erythromycin/Ketoconazole
May increase fexofenadine plasma levels.
Aluminum and Magnesium containing antacids
May decrease fexofenadine absorption if taken concurrently. Separate administration by at least 2 hours.
Storage
Store below 30°C in a dry place, away from light and moisture. Keep out of reach of children.
Overdose
Symptoms of overdose may include dizziness, drowsiness, and dry mouth. Treatment is symptomatic and supportive. Gastric lavage and activated charcoal may be considered.
Pregnancy & Lactation
Pregnancy Category C. Use only if potential benefit justifies potential risk to the fetus. It is unknown if fexofenadine is excreted in human milk; caution should be exercised when administered to a nursing mother.
Frequently Asked Questions
Common questions about this medicine
Pack Sizes
Shelf Life
36 months
Availability
Available in pharmacies nationwide
Approval Status
Approved by health authorities (e.g., FDA, DGDA)
Patent Status
Off-patent
Clinical Trials
Extensive clinical trials have demonstrated Fd-120's efficacy and safety in treating seasonal allergic rhinitis and chronic idiopathic urticaria across various patient populations.
Lab Monitoring
- No specific laboratory monitoring is generally required for routine use.
Doctor Notes
- Advise patients to avoid taking with fruit juices.
- Emphasize non-sedating nature but counsel on individual variability.
- Consider renal dose adjustment for impaired kidney function.
Patient Guidelines
- Take as directed by your doctor.
- Do not exceed the recommended dose.
- Avoid fruit juices.
- Inform your doctor about all other medications you are taking.
Missed Dose Advice
If a dose is missed, take it as soon as you remember. If it is almost time for the next dose, skip the missed dose and resume your regular dosing schedule. Do not take a double dose to make up for a missed one.
Driving Precautions
Fd-120 is generally non-sedating, but individual responses can vary. Caution is advised when driving or operating machinery until you know how this medicine affects you.
Lifestyle Advice
- Identify and avoid allergy triggers.
- Maintain good indoor air quality.
- Stay hydrated.
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Global Brand Names
International brand names for this medicine. Click a brand to search for detailed information.