Felbo
Generic Name
Flurbiprofen 3% Topical Gel
Manufacturer
Example Pharma Ltd.
Country
Bangladesh
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Price Details
Current market pricing information
| Variant | Unit Price | Strip Price |
|---|---|---|
| felbo 3 topical gel | ৳ 300.00 | N/A |
Description
Overview of the medicine
Felbo-3 Topical Gel contains Flurbiprofen 3% w/w, a non-steroidal anti-inflammatory drug (NSAID), used for local relief of pain and inflammation in conditions like musculoskeletal pain, sprains, strains, and osteoarthritis.
Uses & Indications
Dosage
Adults
Apply 2-4 cm of gel to the affected area 2-3 times daily, rubbing gently.
Elderly
No specific dosage adjustment required, but caution is advised.
Renal_impairment
Limited systemic absorption, so dosage adjustment generally not necessary, but use with caution in severe cases.
How to Take
For external use only. Apply a small amount of gel to the affected area and rub it gently until it is absorbed. Wash hands thoroughly after application.
Mechanism of Action
Flurbiprofen inhibits prostaglandin synthesis by reversibly inhibiting cyclooxygenase (COX-1 and COX-2) enzymes. This reduces the formation of inflammatory mediators, thereby decreasing pain, inflammation, and swelling at the site of application.
Pharmacokinetics
Onset
Within 30-60 minutes locally
Excretion
Mainly via urine as metabolites.
Half life
Approximately 3-6 hours (systemic)
Absorption
Limited systemic absorption after topical application. A small fraction penetrates the skin and reaches local tissues and synovial fluid.
Metabolism
Primarily hepatic, mainly to 4'-hydroxyflurbiprofen (inactive metabolite)
Side Effects
Contraindications
- •Hypersensitivity to flurbiprofen or other NSAIDs, including aspirin
- •Patients with asthma, urticaria, or allergic-type reactions after taking aspirin or other NSAIDs
- •Third trimester of pregnancy
- •Application to open wounds, infected skin, eczema, or mucous membranes
Drug Interactions
Other NSAIDs
Concurrent use of systemic NSAIDs may increase risk of adverse effects.
Oral Anticoagulants
Increased risk of bleeding if significant systemic absorption occurs.
Diuretics/ACE inhibitors
May reduce the natriuretic effect of diuretics and the antihypertensive effect of ACE inhibitors.
Storage
Store below 30°C in a dry place, away from direct sunlight. Do not freeze. Keep out of reach of children.
Overdose
Overdose with topical application is unlikely due to minimal systemic absorption. In case of accidental ingestion or excessive application, symptomatic and supportive measures should be taken. Gastric decontamination may be considered if ingested.
Pregnancy & Lactation
Avoid during the third trimester of pregnancy. Use during the first two trimesters and during lactation only if clearly necessary and potential benefits outweigh risks, under medical supervision, due to limited systemic absorption.
Frequently Asked Questions
Common questions about this medicine
Pack Sizes
Shelf Life
Typically 2-3 years from manufacturing date.
Availability
Pharmacies, drugstores
Approval Status
Approved by regulatory bodies
Patent Status
Generic available (Patent expired)
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Global Brand Names
International brand names for this medicine
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