Fenaton
Generic Name
fenaton-500-mg-tablet
Manufacturer
Generic Pharma Ltd.
Country
Bangladesh
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Price Details
Current market pricing information
| Variant | Unit Price | Strip Price |
|---|---|---|
| fenaton 500 mg tablet | ৳ 3.00 | ৳ 30.00 |
Description
Overview of the medicine
Fenaton 500 mg Tablet is a medication primarily used to relieve mild to moderate pain and reduce fever. It is believed to work by inhibiting the production of certain chemical messengers in the brain that are responsible for pain and fever.
Uses & Indications
Dosage
Adults
1-2 tablets (500-1000 mg) every 4-6 hours as needed, not exceeding 4000 mg (8 tablets) in 24 hours.
Elderly
No specific dose adjustment is usually necessary, but caution is advised in patients with compromised renal or hepatic function.
Renal_impairment
Dosage interval may need to be extended in severe renal impairment (e.g., creatinine clearance <10 mL/min).
How to Take
Fenaton 500 mg Tablet should be taken orally with water, with or without food. Do not chew or crush the tablet. Do not exceed the recommended dose.
Mechanism of Action
Fenaton is thought to exert its analgesic and antipyretic effects primarily through the inhibition of prostaglandin synthesis in the central nervous system. It weakly inhibits peripheral prostaglandin synthesis, contributing to minimal anti-inflammatory action.
Pharmacokinetics
Onset
30-60 minutes
Excretion
Mainly excreted in urine as glucuronide and sulfate conjugates; less than 5% is excreted unchanged.
Half life
1.25 to 3 hours
Absorption
Rapidly and almost completely absorbed from the gastrointestinal tract; peak plasma concentrations occur within 30-60 minutes.
Metabolism
Primarily metabolized in the liver via glucuronidation and sulfation, and a small amount via cytochrome P450 pathway to a toxic intermediate (NAPQI) which is rapidly detoxified by glutathione.
Side Effects
Contraindications
- Hypersensitivity to Fenaton or any component of the formulation.
- Severe hepatic impairment or active liver disease.
Drug Interactions
Alcohol
Increased risk of liver damage (hepatotoxicity), especially with chronic heavy alcohol use.
Warfarin
May enhance anticoagulant effect, increasing risk of bleeding. Close monitoring of INR is advised.
Cholestyramine
May reduce the absorption of Fenaton if taken within an hour of each other.
Certain anticonvulsants (e.g., Carbamazepine, Phenytoin)
May increase the risk of liver toxicity due to induction of metabolic enzymes.
Storage
Store in a cool, dry place, below 30°C (86°F). Protect from light and moisture. Keep out of reach of children.
Overdose
Symptoms of overdose include nausea, vomiting, abdominal pain, and delayed onset of liver damage (hepatotoxicity). Seek immediate medical attention. Treatment involves gastric lavage and administration of N-acetylcysteine (NAC) as an antidote.
Pregnancy & Lactation
Generally considered safe for use during pregnancy and lactation when used at recommended doses and for short periods. However, always consult a doctor before use.
Side Effects
Contraindications
- Hypersensitivity to Fenaton or any component of the formulation.
- Severe hepatic impairment or active liver disease.
Drug Interactions
Alcohol
Increased risk of liver damage (hepatotoxicity), especially with chronic heavy alcohol use.
Warfarin
May enhance anticoagulant effect, increasing risk of bleeding. Close monitoring of INR is advised.
Cholestyramine
May reduce the absorption of Fenaton if taken within an hour of each other.
Certain anticonvulsants (e.g., Carbamazepine, Phenytoin)
May increase the risk of liver toxicity due to induction of metabolic enzymes.
Storage
Store in a cool, dry place, below 30°C (86°F). Protect from light and moisture. Keep out of reach of children.
Overdose
Symptoms of overdose include nausea, vomiting, abdominal pain, and delayed onset of liver damage (hepatotoxicity). Seek immediate medical attention. Treatment involves gastric lavage and administration of N-acetylcysteine (NAC) as an antidote.
Pregnancy & Lactation
Generally considered safe for use during pregnancy and lactation when used at recommended doses and for short periods. However, always consult a doctor before use.
Frequently Asked Questions
Common questions about this medicine
Pack Sizes
Shelf Life
24 to 36 months from manufacturing date, depending on specific formulation and manufacturer.
Availability
Pharmacies, drugstores
Approval Status
Approved (Hypothetical)
Patent Status
Expired
WHO Essential Medicine
YesClinical Trials
Fenaton (assuming Paracetamol) has been extensively studied and is one of the most widely used and well-established medications globally. Numerous clinical trials confirm its efficacy and safety profile for its indicated uses.
Lab Monitoring
- Liver function tests (ALT, AST, bilirubin) are recommended, especially with prolonged use, high doses, or in patients with pre-existing liver conditions.
- Renal function tests (serum creatinine, BUN) may be considered in patients with kidney impairment or chronic use.
Doctor Notes
- Emphasize strict adherence to dosing limits to prevent acute liver failure.
- Assess patients for chronic alcohol use or pre-existing liver/renal disease before recommending prolonged use.
- Advise patients about potential interactions with warfarin and the need for INR monitoring.
Patient Guidelines
- Always follow the dosage instructions on the label or as prescribed by your doctor.
- Do not exceed the maximum daily dose to prevent liver damage.
- Avoid taking other products containing Fenaton simultaneously to avoid overdose.
- Consult a doctor if pain or fever persists for more than a few days, or if symptoms worsen.
Missed Dose Advice
If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and resume your regular dosing schedule. Do not take a double dose to make up for a missed one.
Driving Precautions
Fenaton is generally not associated with drowsiness or impaired driving ability at recommended doses. However, if you experience dizziness or drowsiness, avoid driving or operating machinery.
Lifestyle Advice
- Maintain adequate hydration, especially when experiencing fever.
- Ensure sufficient rest to support recovery from pain or fever.
- Avoid alcohol consumption while taking this medication, particularly with chronic use.
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Global Brand Names
International brand names for this medicine. Click a brand to search for detailed information.