Ferdin
Generic Name
Fexofenadine Hydrochloride
Manufacturer
XYZ Pharmaceuticals
Country
Bangladesh
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Price Details
Current market pricing information
| Variant | Unit Price | Strip Price |
|---|---|---|
| ferdin 120 mg tablet | ৳ 7.00 | ৳ 70.00 |
Description
Overview of the medicine
Ferdin 120 mg Tablet contains Fexofenadine Hydrochloride, a second-generation antihistamine used to relieve symptoms of seasonal allergic rhinitis and chronic idiopathic urticaria.
Uses & Indications
Dosage
Adults
120 mg once daily.
Elderly
No dosage adjustment generally required, but caution is advised.
Renal_impairment
Initially 60 mg once daily for patients with impaired renal function (creatinine clearance < 80 mL/min).
How to Take
Take orally with water, usually once daily. Can be taken with or without food. Avoid taking with fruit juices.
Mechanism of Action
Fexofenadine is a selective peripheral H1-receptor antagonist. It competitively inhibits the binding of histamine to H1 receptors, thereby preventing the actions of histamine such as vasodilation, increased vascular permeability, and itching, without causing significant sedation or anticholinergic effects due to its low penetration of the blood-brain barrier.
Pharmacokinetics
Onset
Onset of action within 1 hour.
Excretion
Primarily excreted unchanged via feces (80%) and urine (11%).
Half life
Approximately 14-16 hours.
Absorption
Rapidly absorbed after oral administration, peak plasma concentrations reached in 1-3 hours.
Metabolism
Minimally metabolized; hepatic metabolism is negligible.
Side Effects
Contraindications
- •Hypersensitivity to Fexofenadine or any excipients.
- •Children under 6 years of age for seasonal allergic rhinitis.
Drug Interactions
Erythromycin or Ketoconazole
May increase fexofenadine plasma levels.
Antacids containing aluminum and magnesium
May decrease absorption of fexofenadine. Separate administration by 2 hours.
Storage
Store below 30°C in a dry place, away from light and moisture. Keep out of reach of children.
Overdose
Symptoms include dizziness, drowsiness, and dry mouth. Management is symptomatic and supportive; no specific antidote.
Pregnancy & Lactation
Use during pregnancy only if clearly needed. Excreted in breast milk, caution is advised for nursing mothers.
Frequently Asked Questions
Common questions about this medicine
Pack Sizes
Shelf Life
24-36 months
Availability
Pharmacies nationwide
Approval Status
Approved by regulatory authorities
Patent Status
Off-patent
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Global Brand Names
International brand names for this medicine
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