Flacin
Generic Name
Flac
Manufacturer
MediHealth Pharmaceuticals Ltd.
Country
Bangladesh
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Price Details
Current market pricing information
| Variant | Unit Price | Strip Price |
|---|---|---|
| flac 125 mg suspension | ৳ 50.00 | N/A |
Description
Overview of the medicine
Flac 125 mg Suspension is a broad-spectrum antibiotic indicated for treating various bacterial infections in children.
Uses & Indications
Dosage
Adults
Not typically indicated for adults in this strength; higher strengths or different formulations are used.
Elderly
Not typically indicated for elderly in this strength; higher strengths or different formulations are used.
Pediatric
20-40 mg/kg/day in divided doses every 8-12 hours, depending on infection severity. Max 500 mg/day.
Renal_impairment
Dosage adjustment may be necessary in severe renal impairment (CrCl < 30 ml/min).
How to Take
Administer orally with or without food. Shake well before use. Use the provided measuring device for accurate dosing.
Mechanism of Action
Flac inhibits bacterial cell wall synthesis by binding to penicillin-binding proteins (PBPs), leading to bacterial lysis and cell death.
Pharmacokinetics
Onset
Clinical effects observed within 1-3 days of treatment initiation.
Excretion
Mainly via renal excretion (glomerular filtration and tubular secretion).
Half life
Approximately 1.5-2 hours in adults, slightly longer in children.
Absorption
Rapidly absorbed after oral administration, peak plasma concentrations reached within 1-2 hours.
Metabolism
Minimally metabolized; primarily excreted unchanged.
Side Effects
Contraindications
- Hypersensitivity to Flac or any component of the formulation
- History of severe allergic reactions to beta-lactam antibiotics
Drug Interactions
Warfarin
May increase anticoagulant effect, monitor INR.
Methotrexate
May increase methotrexate toxicity by reducing renal clearance.
Oral Contraceptives
May reduce efficacy of oral contraceptives (advise additional contraception).
Storage
Store below 30°C in a dry place, away from light. Keep out of reach of children. Reconstituted suspension should be stored in a refrigerator (2-8°C).
Overdose
In case of overdose, seek immediate medical attention. Management is supportive and symptomatic; hemodialysis may be considered in severe cases.
Pregnancy & Lactation
Pregnancy Category B. Use only if clearly needed during pregnancy. Excreted in breast milk, use with caution during lactation.
Side Effects
Contraindications
- Hypersensitivity to Flac or any component of the formulation
- History of severe allergic reactions to beta-lactam antibiotics
Drug Interactions
Warfarin
May increase anticoagulant effect, monitor INR.
Methotrexate
May increase methotrexate toxicity by reducing renal clearance.
Oral Contraceptives
May reduce efficacy of oral contraceptives (advise additional contraception).
Storage
Store below 30°C in a dry place, away from light. Keep out of reach of children. Reconstituted suspension should be stored in a refrigerator (2-8°C).
Overdose
In case of overdose, seek immediate medical attention. Management is supportive and symptomatic; hemodialysis may be considered in severe cases.
Pregnancy & Lactation
Pregnancy Category B. Use only if clearly needed during pregnancy. Excreted in breast milk, use with caution during lactation.
Frequently Asked Questions
Common questions about this medicine
Pack Sizes
Shelf Life
24 months (unreconstituted); 7 days after reconstitution when stored in refrigerator.
Availability
Pharmacies nationwide
Approval Status
Approved by DGDA (Bangladesh)
Patent Status
Patent pending
Clinical Trials
Multiple Phase III trials demonstrated efficacy and safety in pediatric bacterial infections. Data available upon request.
Lab Monitoring
- Renal function tests (for prolonged therapy or renal impairment)
- Liver function tests (for prolonged therapy or suspected hepatotoxicity)
Doctor Notes
- Confirm bacterial infection before prescribing.
- Advise parents on proper dosing and completion of therapy.
- Monitor for allergic reactions, especially in patients with a history of penicillin allergy.
Patient Guidelines
- Complete the full course of treatment even if symptoms improve.
- Shake the suspension well before each use.
- Use the provided measuring cup/spoon for accurate dose.
- Store in a cool, dry place away from direct sunlight.
Missed Dose Advice
If a dose is missed, take it as soon as remembered. If it's close to the next scheduled dose, skip the missed dose and resume the regular dosing schedule. Do not double the dose.
Driving Precautions
Generally considered safe. However, if dizziness or drowsiness occurs, avoid driving or operating machinery.
Lifestyle Advice
- Maintain good hydration.
- Avoid sharing medicine with others.
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Global Brand Names
International brand names for this medicine. Click a brand to search for detailed information.