Flexor
Generic Name
flexor-5-mg-tablet
Manufacturer
Generic Pharma Ltd.
Country
Bangladesh
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Price Details
Current market pricing information
| Variant | Unit Price | Strip Price |
|---|---|---|
| flexor 5 mg tablet | ৳ 2.00 | ৳ 20.00 |
Description
Overview of the medicine
Flexor 5 mg tablet is a muscle relaxant used to relieve pain, discomfort, and stiffness associated with acute, painful musculoskeletal conditions.
Uses & Indications
Dosage
Adults
The usual dose is 5 mg three times a day. Based on individual patient response, the dose may be increased to 10 mg three times a day. Do not exceed a total daily dose of 30 mg.
Elderly
Initiate with 5 mg once a day and gradually titrate upwards. Monitor for sedation and anticholinergic effects.
Renal_impairment
Use with caution. Dose adjustment may be necessary in patients with severe renal impairment due to potential accumulation of metabolites.
How to Take
Flexor tablets can be taken orally, with or without food. Swallow the tablet whole with a glass of water. Do not crush or chew.
Mechanism of Action
Flexor works as a centrally acting skeletal muscle relaxant. It reduces tonic somatic motor activity influencing both alpha and gamma motor systems. It's thought to act primarily at the brain stem level, reducing muscle spasm without interfering with muscle function.
Pharmacokinetics
Onset
Onset of action typically within 1 hour.
Excretion
Excreted primarily via the kidneys as metabolites.
Half life
Mean plasma half-life is 18 hours (range 8-37 hours).
Absorption
Rapidly and well absorbed from the gastrointestinal tract. Peak plasma concentrations are reached in about 2 to 8 hours.
Metabolism
Extensively metabolized in the liver, primarily by oxidation followed by conjugation.
Side Effects
Contraindications
- Hypersensitivity to Flexor or any components of the tablet
- Concomitant use of monoamine oxidase inhibitors (MAOIs) or within 14 days of discontinuing MAOIs
- Hyperthyroidism
- Acute recovery phase of myocardial infarction
- Heart block, conduction disturbances, or arrhythmias
Drug Interactions
MAOIs
Concomitant use may lead to hyperpyretic crises, severe convulsions, and death.
Tricyclic Antidepressants (TCAs)
May potentiate the risk of adverse effects due to structural similarity.
CNS Depressants (e.g., alcohol, barbiturates, benzodiazepines)
May enhance the depressant effects on the central nervous system.
Storage
Store at controlled room temperature (20-25°C), away from moisture, heat, and direct light. Keep out of reach of children.
Overdose
Symptoms of overdose include drowsiness, hypothermia, tachycardia, and other anticholinergic effects. Management involves symptomatic and supportive treatment. Gastric lavage may be considered if performed early.
Pregnancy & Lactation
Pregnancy Category B. Studies in animals have shown no evidence of harm to the fetus, but there are no adequate and well-controlled studies in pregnant women. Use during pregnancy only if clearly needed. It is not known whether Flexor is excreted in human milk; caution should be exercised when administered to a nursing woman.
Side Effects
Contraindications
- Hypersensitivity to Flexor or any components of the tablet
- Concomitant use of monoamine oxidase inhibitors (MAOIs) or within 14 days of discontinuing MAOIs
- Hyperthyroidism
- Acute recovery phase of myocardial infarction
- Heart block, conduction disturbances, or arrhythmias
Drug Interactions
MAOIs
Concomitant use may lead to hyperpyretic crises, severe convulsions, and death.
Tricyclic Antidepressants (TCAs)
May potentiate the risk of adverse effects due to structural similarity.
CNS Depressants (e.g., alcohol, barbiturates, benzodiazepines)
May enhance the depressant effects on the central nervous system.
Storage
Store at controlled room temperature (20-25°C), away from moisture, heat, and direct light. Keep out of reach of children.
Overdose
Symptoms of overdose include drowsiness, hypothermia, tachycardia, and other anticholinergic effects. Management involves symptomatic and supportive treatment. Gastric lavage may be considered if performed early.
Pregnancy & Lactation
Pregnancy Category B. Studies in animals have shown no evidence of harm to the fetus, but there are no adequate and well-controlled studies in pregnant women. Use during pregnancy only if clearly needed. It is not known whether Flexor is excreted in human milk; caution should be exercised when administered to a nursing woman.
Frequently Asked Questions
Common questions about this medicine
Pack Sizes
Shelf Life
24 months from the date of manufacture.
Availability
Available in pharmacies
Approval Status
Approved by FDA
Patent Status
Expired
Clinical Trials
Clinical trials have demonstrated the effectiveness of Flexor in reducing muscle spasm and associated pain in patients with acute musculoskeletal conditions for short-term treatment. Its efficacy for long-term use has not been established.
Lab Monitoring
- Routine lab monitoring is generally not required for Flexor 5 mg tablet. Liver function tests may be considered in patients with pre-existing hepatic impairment or during prolonged use.
Doctor Notes
- Prescribe for short-term use (up to 2-3 weeks) only.
- Caution in elderly patients due to increased risk of sedation and anticholinergic effects.
- Advise patients about potential drowsiness and to avoid activities requiring mental alertness.
Patient Guidelines
- Do not drive or operate heavy machinery if you experience drowsiness or dizziness.
- Avoid alcohol consumption while taking this medication.
- Take the medication for the prescribed duration, usually short-term (2-3 weeks).
- Inform your doctor about all other medications you are taking.
Missed Dose Advice
If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and resume your regular dosing schedule. Do not take a double dose to make up for a missed one.
Driving Precautions
Flexor may cause drowsiness, dizziness, or blurred vision. Patients should be cautioned about engaging in activities requiring mental alertness, such as operating a motor vehicle or hazardous machinery, until they know how the drug affects them.
Lifestyle Advice
- In addition to medication, incorporating rest, physical therapy, and proper posture can aid in recovery from musculoskeletal pain.
- Avoid activities that exacerbate your muscle pain.
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Global Brand Names
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