Take the tablet orally, preferably with food or milk, to minimize gastrointestinal upset. Swallow whole with a glass of water; do not crush or chew.

Flogem acts by inhibiting cyclooxygenase (COX-1 and COX-2) enzymes, which are responsible for the synthesis of prostaglandins from arachidonic acid. Prostaglandins mediate inflammation, pain, and fever.

• •Known hypersensitivity to Flogem or other NSAIDs (e.g., aspirin-induced asthma, urticaria)
• •Active gastrointestinal bleeding or peptic ulcer disease
• •Severe renal or hepatic impairment
• •Severe heart failure
• •Third trimester of pregnancy

Store in a cool, dry place, away from direct sunlight and moisture. Keep out of reach of children.

Symptoms of overdose may include nausea, vomiting, epigastric pain, lethargy, drowsiness, and gastrointestinal bleeding. Management involves symptomatic and supportive treatment, gastric lavage, activated charcoal, and monitoring vital signs.

Avoid Flogem during the third trimester of pregnancy due to potential fetal harm (premature closure of ductus arteriosus). Use with caution in the first and second trimesters and during lactation only if the potential benefit outweighs the risk. Consult a doctor.