Flupion
Generic Name
Fluocinolone Acetonide 0.05% Ointment
Manufacturer
Generic Pharma Ltd.
Country
Bangladesh
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Price Details
Current market pricing information
| Variant | Unit Price | Strip Price |
|---|---|---|
| flupion 0005 ointment | ৳ 50.00 | N/A |
Description
Overview of the medicine
Flupion-0005-ointment is a topical corticosteroid used to reduce inflammation, itching, and redness associated with various skin conditions.
Uses & Indications
Dosage
Adults
Apply a thin film to the affected skin area 2 to 3 times daily, or as directed by a physician. Rub in gently.
Elderly
No specific dosage adjustments required; use with caution for prolonged periods or on large areas due to potential for increased systemic absorption.
Renal_impairment
No specific dosage adjustments required for topical use, as systemic absorption is minimal.
How to Take
For external use only. Apply a thin layer to the affected skin area and rub in gently. Wash hands before and after application.
Mechanism of Action
Fluocinolone acetonide, a corticosteroid, acts by inducing phospholipase A2 inhibitory proteins, thereby controlling the biosynthesis of potent mediators of inflammation such as prostaglandins and leukotrienes.
Pharmacokinetics
Onset
Within hours to days of application.
Excretion
Excreted by the kidneys and in bile.
Half life
Not precisely determined for topical application, but systemic elimination is relatively rapid.
Absorption
Systemic absorption occurs to some extent, especially with prolonged use, large surface areas, or occlusive dressings.
Metabolism
Primarily metabolized in the liver.
Side Effects
Contraindications
- Hypersensitivity to fluocinolone acetonide or any component of the formulation.
- Primary cutaneous viral infections (e.g., herpes simplex, varicella).
- Fungal or bacterial infections of the skin unless used concurrently with appropriate anti-infective therapy.
- Perioral dermatitis, rosacea, acne vulgaris.
- Anogenital pruritus without inflammation.
Drug Interactions
Other topical corticosteroids
Concurrent use may increase systemic absorption and risk of side effects.
Corticosteroid receptor modulators
Potential for altered effects with systemic agents, though minimal for topical use.
Storage
Store below 30°C in a dry place, away from light. Do not freeze. Keep out of reach of children.
Overdose
Acute overdose with topical application is unlikely. Chronic overuse may lead to Cushing's syndrome, hyperglycemia, and glucosuria.
Pregnancy & Lactation
Use in pregnancy and lactation only if the potential benefit justifies the potential risk to the fetus or infant. Consult a doctor.
Side Effects
Contraindications
- Hypersensitivity to fluocinolone acetonide or any component of the formulation.
- Primary cutaneous viral infections (e.g., herpes simplex, varicella).
- Fungal or bacterial infections of the skin unless used concurrently with appropriate anti-infective therapy.
- Perioral dermatitis, rosacea, acne vulgaris.
- Anogenital pruritus without inflammation.
Drug Interactions
Other topical corticosteroids
Concurrent use may increase systemic absorption and risk of side effects.
Corticosteroid receptor modulators
Potential for altered effects with systemic agents, though minimal for topical use.
Storage
Store below 30°C in a dry place, away from light. Do not freeze. Keep out of reach of children.
Overdose
Acute overdose with topical application is unlikely. Chronic overuse may lead to Cushing's syndrome, hyperglycemia, and glucosuria.
Pregnancy & Lactation
Use in pregnancy and lactation only if the potential benefit justifies the potential risk to the fetus or infant. Consult a doctor.
Frequently Asked Questions
Common questions about this medicine
Pack Sizes
Shelf Life
36 months
Availability
Pharmacies, Hospitals
Approval Status
Approved (generic)
Patent Status
Generic available
Clinical Trials
Fluocinolone acetonide has been extensively studied for its efficacy and safety in various dermatological conditions in numerous clinical trials.
Lab Monitoring
- Routine lab monitoring is generally not required for topical use. Adrenal function tests may be considered in cases of extensive and prolonged use, especially in children.
Doctor Notes
- Prescribe for shortest effective duration.
- Avoid use on face, axillae, groin due to increased risk of atrophy and striae.
- Educate patients on proper application technique and potential side effects.
Patient Guidelines
- Use only as directed by your doctor.
- Do not apply to the face, groin, or underarms unless specifically instructed by your doctor.
- Avoid contact with eyes and mucous membranes.
- Do not use for longer than the prescribed period.
- Do not bandage or cover the treated area unless directed by your doctor.
Missed Dose Advice
If you miss a dose, apply it as soon as you remember. Do not apply extra medicine to make up for a missed dose.
Driving Precautions
Flupion-0005-ointment is unlikely to affect the ability to drive or operate machinery.
Lifestyle Advice
- Keep skin moisturized to prevent dryness.
- Avoid irritants and allergens that may worsen skin conditions.
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Global Brand Names
International brand names for this medicine. Click a brand to search for detailed information.