Fresh
Generic Name
Fresh-05-mg-tablet
Manufacturer
MediCare Pharma Ltd.
Country
Bangladesh
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Price Details
Current market pricing information
| Variant | Unit Price | Strip Price |
|---|---|---|
| fresh 05 mg tablet | ৳ 0.80 | ৳ 8.00 |
Description
Overview of the medicine
Fresh-0.5 mg Tablet is an anxiolytic medication used for the short-term relief of symptoms of anxiety and panic disorders. It helps to calm the brain and nerves.
Uses & Indications
Dosage
Adults
Initially 0.25-0.5 mg three times daily, adjusted according to patient response and tolerability, up to a maximum of 4 mg daily.
Elderly
Lower initial doses (e.g., 0.25 mg two to three times daily) are recommended, with careful titration.
Renal_impairment
No specific dose adjustment guidelines; use with caution. Consider lower initial doses.
How to Take
Take Fresh-0.5 mg Tablet orally with water, with or without food. Do not chew or crush the tablet. Follow your doctor's instructions carefully.
Mechanism of Action
Fresh-0.5 mg Tablet is thought to act by enhancing the effect of certain natural chemical messengers (GABA) in the brain, thereby producing a calming effect on the central nervous system.
Pharmacokinetics
Onset
Within 30-60 minutes.
Excretion
Excreted mainly in the urine as metabolites, with a small portion excreted in feces.
Half life
Approximately 10-15 hours.
Absorption
Rapidly absorbed after oral administration, peak plasma concentrations reached within 1-2 hours.
Metabolism
Primarily metabolized in the liver via oxidative pathways, forming active and inactive metabolites.
Side Effects
Contraindications
- •Known hypersensitivity to Fresh-0.5 mg Tablet or any component of the formulation
- •Acute narrow-angle glaucoma
- •Severe respiratory insufficiency
Drug Interactions
Opioids
Increased risk of sedation, respiratory depression, coma, and death.
Fluoxetine, Fluvoxamine
May alter metabolism and increase exposure.
Ketoconazole, Itraconazole
May increase plasma concentration of Fresh-0.5 mg Tablet.
Alcohol and other CNS depressants
Potentiation of CNS depressant effects.
Storage
Store in a cool, dry place below 30°C. Protect from light and moisture. Keep out of reach of children.
Overdose
Symptoms of overdose include drowsiness, confusion, impaired coordination, diminished reflexes, and coma. Treatment is primarily supportive; maintain airway, monitor vital signs, and consider activated charcoal. Flumazenil may be used as an antidote in severe cases but carries risks.
Pregnancy & Lactation
Pregnancy Category D. Fresh-0.5 mg Tablet should be avoided during pregnancy due to potential risks to the fetus. It is excreted in breast milk and should not be used during lactation.
Frequently Asked Questions
Common questions about this medicine
Pack Sizes
Shelf Life
24 months from the date of manufacture.
Availability
Available in pharmacies nationwide
Approval Status
Approved by DGDA
Patent Status
Patented
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Global Brand Names
International brand names for this medicine
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