Fucidin
Generic Name
Fusidic Acid 2% Ointment
Manufacturer
LEO Pharma (original developer), various generics
Country
Denmark (original), various for generics
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Price Details
Current market pricing information
| Variant | Unit Price | Strip Price |
|---|---|---|
| fusidate 2 ointment | ৳ 85.00 | N/A |
Description
Overview of the medicine
Fusidic acid 2% ointment is a topical antibiotic used to treat bacterial skin infections caused by susceptible organisms, primarily Staphylococcus species.
Uses & Indications
Dosage
Adults
Apply a thin layer to the affected area 2-3 times daily, generally for 7 days. Treatment duration should not exceed 10 days.
Elderly
No specific dosage adjustment required.
Renal_impairment
No specific dosage adjustment required due to minimal systemic absorption.
How to Take
For external use only. Clean the affected area thoroughly before applying a thin layer of ointment. Wash hands before and after application.
Mechanism of Action
Fusidic acid inhibits bacterial protein synthesis by interfering with the translocation of elongation factor G (EF-G) from the ribosome, preventing bacterial growth and replication.
Pharmacokinetics
Onset
Within hours to days of application.
Excretion
Mainly through bile and feces if systemically absorbed.
Half life
Not applicable for topical use due to minimal systemic absorption.
Absorption
Minimal systemic absorption through intact skin. Absorption may increase if applied to damaged skin.
Metabolism
Primarily hepatic if significant systemic absorption occurs (rare with topical use).
Side Effects
Contraindications
- Hypersensitivity to fusidic acid or any other components of the ointment.
- Infections caused by non-susceptible organisms.
Drug Interactions
Systemic antibiotics
Minimal systemic absorption, so drug interactions are unlikely with topical application.
Storage
Store below 25-30°C. Do not freeze. Keep out of direct sunlight and moisture. Keep out of reach of children.
Overdose
Topical overdose is unlikely to cause systemic effects due to minimal absorption. Excessive application may lead to increased local irritation.
Pregnancy & Lactation
Use with caution in pregnant and breastfeeding women only if clearly needed and after consulting a doctor, as systemic absorption is minimal.
Side Effects
Contraindications
- Hypersensitivity to fusidic acid or any other components of the ointment.
- Infections caused by non-susceptible organisms.
Drug Interactions
Systemic antibiotics
Minimal systemic absorption, so drug interactions are unlikely with topical application.
Storage
Store below 25-30°C. Do not freeze. Keep out of direct sunlight and moisture. Keep out of reach of children.
Overdose
Topical overdose is unlikely to cause systemic effects due to minimal absorption. Excessive application may lead to increased local irritation.
Pregnancy & Lactation
Use with caution in pregnant and breastfeeding women only if clearly needed and after consulting a doctor, as systemic absorption is minimal.
Frequently Asked Questions
Common questions about this medicine
Pack Sizes
Shelf Life
Typically 24-36 months when stored unopened.
Availability
Pharmacies, hospitals, clinics
Approval Status
Approved (internationally)
Patent Status
Generic available
WHO Essential Medicine
YesClinical Trials
Numerous clinical trials have established the efficacy and safety of fusidic acid for various bacterial skin infections since its introduction.
Lab Monitoring
- Not routinely required for topical use.
Doctor Notes
- Advise patients to complete the full course of treatment even if symptoms improve.
- Emphasize correct application technique to maximize efficacy and minimize side effects.
- Counsel on signs of allergic reactions and when to seek medical attention.
Patient Guidelines
- Wash hands thoroughly before and after applying the ointment.
- Do not use for longer than 10 days unless advised by a doctor.
- Avoid contact with eyes.
- If irritation persists, discontinue use and consult a doctor.
Missed Dose Advice
If a dose is missed, apply it as soon as you remember. Do not apply a double dose to make up for a missed one.
Driving Precautions
No known effects on ability to drive or operate machinery with topical application.
Lifestyle Advice
- Maintain good personal hygiene to prevent recurrence of infections.
- Keep the infected area clean and dry.
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Global Brand Names
International brand names for this medicine. Click a brand to search for detailed information.
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