G-Antacid
Generic Name
Aluminium Hydroxide, Magnesium Hydroxide, Simethicone
Manufacturer
General Pharmaceutical Company
Country
Bangladesh
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Price Details
Current market pricing information
| Variant | Unit Price | Strip Price |
|---|---|---|
| g antacid 250 mg chewable tablet | ৳ 0.50 | ৳ 5.00 |
Description
Overview of the medicine
G-Antacid is a combination medicine used to relieve symptoms of heartburn, indigestion, and gas (flatulence). It contains antacids (aluminium hydroxide and magnesium hydroxide) to neutralize stomach acid and simethicone to break down gas bubbles.
Uses & Indications
Dosage
Adults
10-20 ml (2-4 teaspoonfuls) or 1-2 chewable tablets, 3-4 times daily, after meals and at bedtime.
Elderly
Same as adults, with caution in those with renal impairment.
Renal_impairment
Use with caution. Reduced dosage may be necessary due to risk of hypermagnesemia.
How to Take
For suspension, shake well before use. Take orally after meals and at bedtime. For chewable tablets, chew thoroughly before swallowing.
Mechanism of Action
Aluminium and Magnesium Hydroxides act as antacids by neutralizing hydrochloric acid in the stomach, reducing its acidity. Simethicone acts as an anti-foaming agent, reducing surface tension of gas bubbles in the GI tract, allowing them to combine and be easily expelled.
Pharmacokinetics
Onset
Within minutes
Excretion
Unabsorbed aluminium and magnesium are excreted via feces. Simethicone is excreted unchanged in feces.
Half life
Not applicable for local action; systemic half-life for absorbed ions are short.
Absorption
Minimal systemic absorption for aluminium and magnesium salts. Simethicone is not absorbed from the GI tract.
Metabolism
Not significantly metabolized systemically. Aluminium and magnesium ions are minimally absorbed.
Side Effects
Contraindications
- Hypersensitivity to any component
- Severe renal impairment
- Hypophosphatemia
Drug Interactions
Iron Salts
Decreased absorption of iron. Separate administration by 2-3 hours.
Tetracyclines
Decreased absorption of tetracyclines. Separate administration by 2-3 hours.
Fluoroquinolones
Decreased absorption of fluoroquinolones. Separate administration by 2-3 hours.
Storage
Store below 30°C. Protect from light and moisture. Do not freeze. Keep out of reach of children.
Overdose
Symptoms may include severe constipation or diarrhea, abdominal pain, and in rare cases with severe renal impairment, hypermagnesemia (muscle weakness, hypotension). Treatment is symptomatic and supportive.
Pregnancy & Lactation
Generally considered safe during pregnancy and lactation when used at recommended doses. Consult a doctor before use.
Side Effects
Contraindications
- Hypersensitivity to any component
- Severe renal impairment
- Hypophosphatemia
Drug Interactions
Iron Salts
Decreased absorption of iron. Separate administration by 2-3 hours.
Tetracyclines
Decreased absorption of tetracyclines. Separate administration by 2-3 hours.
Fluoroquinolones
Decreased absorption of fluoroquinolones. Separate administration by 2-3 hours.
Storage
Store below 30°C. Protect from light and moisture. Do not freeze. Keep out of reach of children.
Overdose
Symptoms may include severe constipation or diarrhea, abdominal pain, and in rare cases with severe renal impairment, hypermagnesemia (muscle weakness, hypotension). Treatment is symptomatic and supportive.
Pregnancy & Lactation
Generally considered safe during pregnancy and lactation when used at recommended doses. Consult a doctor before use.
Frequently Asked Questions
Common questions about this medicine
Pack Sizes
Shelf Life
Typically 2-3 years from manufacturing date.
Availability
Available in all pharmacies and drug stores
Approval Status
Approved by DGDA
Patent Status
Expired/Not Applicable (Generic)
WHO Essential Medicine
YesClinical Trials
G-Antacid, being a combination of well-established generic compounds, has not undergone specific recent large-scale clinical trials. Its efficacy is based on the long-standing use and studies of its individual components.
Lab Monitoring
- Serum phosphate levels (with prolonged use)
- Magnesium levels (in patients with renal impairment)
Doctor Notes
- Advise patients to take this medication separate from other drugs to avoid interactions.
- Educate on lifestyle modifications for GERD/indigestion.
- Monitor for signs of electrolyte imbalance, especially in patients with renal dysfunction.
Patient Guidelines
- Shake suspension well before each use.
- Take after meals for best results.
- Do not exceed the recommended dose.
- Consult a doctor if symptoms persist for more than 2 weeks.
Missed Dose Advice
If you miss a dose, take it as soon as you remember, unless it is almost time for your next dose. Do not double the dose to catch up.
Driving Precautions
G-Antacid is not known to affect the ability to drive or operate machinery.
Lifestyle Advice
- Avoid trigger foods (spicy, fatty, acidic foods, caffeine).
- Eat smaller, more frequent meals.
- Do not lie down immediately after eating.
- Elevate head of bed if experiencing nighttime reflux.
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Global Brand Names
International brand names for this medicine. Click a brand to search for detailed information.
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