Gastid (Orange Flavor)
Generic Name
Aluminium Hydroxide + Magnesium Hydroxide (Orange Flavor) 480 mg/5 ml Suspension
Manufacturer
Square Pharmaceuticals Ltd.
Country
Bangladesh
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Price Details
Current market pricing information
| Variant | Unit Price | Strip Price |
|---|---|---|
| gastid orange flavor 480 mg suspension | ৳ 120.00 | N/A |
Description
Overview of the medicine
Gastid (Orange Flavor) 480 mg Suspension is an antacid medication used to relieve symptoms of heartburn, indigestion, and sour stomach. It contains Aluminium Hydroxide and Magnesium Hydroxide, which work by neutralizing stomach acid.
Uses & Indications
Dosage
Adults
10-20 ml (2-4 teaspoonfuls) 3-4 times daily, preferably between meals and at bedtime, or as directed by a physician.
Elderly
No specific dose adjustment is generally required, but caution is advised in elderly patients with impaired renal function.
Renal_impairment
Use with caution in severe renal impairment due to risk of aluminum and magnesium accumulation. Dose reduction may be necessary.
How to Take
Shake the bottle well before each use. Take orally. For best results, take between meals and at bedtime. Do not take with other medications that require stomach acid for absorption, wait at least 2 hours.
Mechanism of Action
Aluminium Hydroxide and Magnesium Hydroxide are inorganic salts that act as antacids. They react with hydrochloric acid in the stomach to form water and other compounds, thereby raising the pH of gastric contents and reducing acidity. Magnesium hydroxide also has a mild laxative effect, while aluminium hydroxide can cause constipation, balancing the overall bowel effect.
Pharmacokinetics
Onset
Within 5-10 minutes.
Excretion
Unabsorbed portions excreted in feces. Small absorbed amounts of magnesium and aluminum are renally excreted.
Half life
Not applicable for local acting antacids; systemic half-life for absorbed ions is short (minutes to hours).
Absorption
Minimal systemic absorption; acts primarily in the gastrointestinal tract.
Metabolism
Not metabolized in the conventional sense; reacts chemically.
Side Effects
Contraindications
- Known hypersensitivity to aluminum hydroxide, magnesium hydroxide, or any component of the formulation.
- Severe renal impairment (risk of hypermagnesemia and aluminum toxicity).
- Hypophosphatemia.
Drug Interactions
Thyroid hormones
Reduced absorption of thyroid hormones. Administer several hours apart.
Iron salts & Digoxin
Reduced absorption. Separate administration by at least 2 hours.
Mycophenolate Mofetil
Reduced absorption. Avoid concomitant use.
Ketoconazole & Itraconazole
Reduced absorption due to increased gastric pH. Avoid concomitant use.
Sodium Polystyrene Sulfonate
Increased risk of intestinal obstruction or necrosis, especially with aluminum-containing antacids.
Tetracyclines & Fluoroquinolones
Reduced absorption of antibiotics due to chelation. Separate administration by at least 2-4 hours.
Storage
Store below 30°C. Protect from light and moisture. Keep out of the reach of children. Do not freeze.
Overdose
Symptoms of overdose may include severe diarrhea, constipation, nausea, vomiting, or abdominal pain. In severe cases or with renal impairment, hypermagnesemia or aluminum toxicity may occur. Treatment involves symptomatic and supportive measures. Dialysis may be required in severe cases of hypermagnesemia or aluminum toxicity.
Pregnancy & Lactation
Generally considered safe for occasional use during pregnancy and lactation, but prolonged high-dose use should be avoided. Consult a doctor before use.
Side Effects
Contraindications
- Known hypersensitivity to aluminum hydroxide, magnesium hydroxide, or any component of the formulation.
- Severe renal impairment (risk of hypermagnesemia and aluminum toxicity).
- Hypophosphatemia.
Drug Interactions
Thyroid hormones
Reduced absorption of thyroid hormones. Administer several hours apart.
Iron salts & Digoxin
Reduced absorption. Separate administration by at least 2 hours.
Mycophenolate Mofetil
Reduced absorption. Avoid concomitant use.
Ketoconazole & Itraconazole
Reduced absorption due to increased gastric pH. Avoid concomitant use.
Sodium Polystyrene Sulfonate
Increased risk of intestinal obstruction or necrosis, especially with aluminum-containing antacids.
Tetracyclines & Fluoroquinolones
Reduced absorption of antibiotics due to chelation. Separate administration by at least 2-4 hours.
Storage
Store below 30°C. Protect from light and moisture. Keep out of the reach of children. Do not freeze.
Overdose
Symptoms of overdose may include severe diarrhea, constipation, nausea, vomiting, or abdominal pain. In severe cases or with renal impairment, hypermagnesemia or aluminum toxicity may occur. Treatment involves symptomatic and supportive measures. Dialysis may be required in severe cases of hypermagnesemia or aluminum toxicity.
Pregnancy & Lactation
Generally considered safe for occasional use during pregnancy and lactation, but prolonged high-dose use should be avoided. Consult a doctor before use.
Frequently Asked Questions
Common questions about this medicine
Pack Sizes
Shelf Life
Typically 2-3 years from manufacturing date. Check expiry date on packaging.
Availability
Pharmacies nationwide
Approval Status
Approved by DGDA (Bangladesh)
Patent Status
Off-patent
WHO Essential Medicine
YesClinical Trials
Extensively studied and widely used antacid combination; efficacy and safety are well-established through historical and ongoing clinical use rather than recent large-scale trials for basic formulations.
Lab Monitoring
- Serum electrolyte levels (magnesium, phosphate) for prolonged use or in patients with renal impairment.
- Renal function tests.
Doctor Notes
- Advise patients to shake well before use.
- Remind patients to separate administration from other oral medications.
- Counsel on lifestyle modifications for indigestion management.
- Monitor for signs of electrolyte imbalance with prolonged use in at-risk patients.
Patient Guidelines
- Shake well before use.
- Take as directed by a healthcare professional.
- Do not exceed recommended dose.
- Separate antacid from other medications by at least 2 hours.
- Consult a doctor if symptoms persist for more than 2 weeks.
Missed Dose Advice
If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for a missed one.
Driving Precautions
Gastid (Orange Flavor) 480 mg Suspension is not known to impair the ability to drive or operate machinery.
Lifestyle Advice
- Avoid foods and drinks that trigger indigestion (e.g., spicy foods, fatty foods, caffeine, alcohol, acidic juices).
- Eat smaller, more frequent meals.
- Avoid lying down immediately after eating.
- Maintain a healthy weight.
- Quit smoking.
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