Gavipres
Generic Name
gavipres-500-mg-suspension
Manufacturer
MediCare Pharma Ltd.
Country
Bangladesh
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Price Details
Current market pricing information
| Variant | Unit Price | Strip Price |
|---|---|---|
| gavipres 500 mg suspension | ৳ 250.00 | N/A |
Description
Overview of the medicine
Gavipres 500 mg Suspension is a broad-spectrum macrolide antibiotic used to treat various bacterial infections in children and adults. It works by stopping the growth of bacteria.
Uses & Indications
Dosage
Adults
500 mg once daily for 3-7 days, depending on infection type.
Elderly
No specific dosage adjustment required, but monitor renal and hepatic function.
Renal_impairment
No dosage adjustment needed for mild to moderate impairment; use with caution in severe impairment.
How to Take
Gavipres suspension should be shaken well before use. It can be taken with or without food. Complete the full course of medication even if symptoms improve.
Mechanism of Action
Gavipres inhibits bacterial protein synthesis by binding to the 50S ribosomal subunit, thereby interfering with the translocation of peptides. This action is primarily bacteriostatic.
Pharmacokinetics
Onset
Within 2-3 hours of administration.
Excretion
Mainly through bile and feces; a small portion is excreted renally.
Half life
Approximately 2-4 hours, variable based on formulation and dosage.
Absorption
Rapidly absorbed from the gastrointestinal tract; absorption may be affected by food.
Metabolism
Primarily hepatic, undergoes extensive first-pass metabolism.
Side Effects
Contraindications
- •Hypersensitivity to Gavipres or any macrolide antibiotic.
- •History of cholestatic jaundice/hepatic dysfunction associated with previous Gavipres use.
Drug Interactions
Antacids
May reduce Gavipres absorption; administer Gavipres at least 2 hours before or 4 hours after antacids.
Warfarin
Increased anticoagulant effect; monitor INR.
Cyclosporine
Increased cyclosporine levels; monitor cyclosporine concentrations.
Storage
Store powder below 30°C, away from moisture and light. Store reconstituted suspension in a refrigerator (2-8°C) or at room temperature (below 30°C) as per manufacturer's instructions, and discard after specified period.
Overdose
Symptoms of overdose include severe nausea, vomiting, diarrhea, and abdominal discomfort. Treatment is symptomatic and supportive; gastric lavage may be considered.
Pregnancy & Lactation
Pregnancy Category B. Use only if clearly needed. Excreted in breast milk; caution advised during lactation.
Frequently Asked Questions
Common questions about this medicine
Pack Sizes
Shelf Life
24 months (unreconstituted powder). Reconstituted suspension is stable for 5-10 days depending on storage conditions.
Availability
Pharmacies, hospitals
Approval Status
Approved by Regulatory Authority
Patent Status
Generic available
WHO Essential Medicine
YesAlternative Medicines in Bangladesh
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Global Brand Names
International brand names for this medicine
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