Medicine Information

Gcool

Name: Gcool
Brand: Gcool
Rating: 4.5 (117 reviews)

Suspension500 mg (per 5ml)AntacidATC: A02AD01

Generic Name

Aluminum Hydroxide & Magnesium Hydroxide

Manufacturer

MediCare Pharma Ltd.

Country

Bangladesh

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Price Details

Current market pricing information

Variant	Unit Price	Strip Price
gcool 500 mg suspension	৳ 300.00	N/A

Description

Overview of the medicine

Gcool 500 mg Suspension is an antacid preparation used to relieve symptoms of heartburn, indigestion, and acid reflux. It contains active ingredients that neutralize stomach acid.

Uses & Indications

Heartburn

Indigestion

Acid reflux

Gastritis

Peptic ulcer disease (symptomatic relief)

Dosage

Adults

10-20 ml (equivalent to 1-2 measuring spoonfuls) four times daily, between meals and at bedtime, or as directed by physician.

Elderly

No specific dose adjustment needed, but caution in renal impairment.

Renal_impairment

Use with caution. Higher risk of hypermagnesemia or aluminum toxicity. Consult a physician.

How to Take

Shake well before use. Take orally, preferably between meals and at bedtime. Do not take within 1-2 hours of other medications.

Mechanism of Action

Antacids work by neutralizing hydrochloric acid in the stomach, thereby increasing the pH of gastric contents. Aluminum hydroxide and magnesium hydroxide act locally in the stomach.

Pharmacokinetics

Onset

Within 5-15 minutes

Excretion

Mainly fecal excretion of unreacted drug; absorbed ions are renally excreted.

Half life

Not applicable for local action; absorbed ions are renally excreted within hours.

Absorption

Minimal systemic absorption of aluminum and magnesium ions, though some magnesium may be absorbed, especially in renal impairment. Local action in the gastrointestinal tract.

Metabolism

Not significantly metabolized; primary action is neutralization.

Side Effects

Contraindications

Hypersensitivity to any component
Severe renal impairment
Hypophosphatemia

Drug Interactions

Digoxin

Decreased absorption of digoxin. Separate administration.

Iron supplements

Decreased absorption of iron. Separate administration.

Tetracyclines & Fluoroquinolones

Decreased absorption due to chelation. Separate administration by at least 2-4 hours.

Storage

Store below 30°C in a dry place, away from light. Do not freeze. Keep out of reach of children.

Overdose

Symptoms may include diarrhea, constipation, nausea, vomiting, abdominal pain. In severe cases with renal impairment, hypermagnesemia (muscle weakness, hypotension, respiratory depression) or aluminum toxicity (osteomalacia, encephalopathy) may occur. Treatment is symptomatic and supportive.

Pregnancy & Lactation

Generally considered safe for use during pregnancy and lactation, but use with caution and consult a doctor. Avoid prolonged use of high doses.

Frequently Asked Questions

Common questions about this medicine

Pack Sizes

100 ml bottle200 ml bottle

Shelf Life

24 months from manufacturing date

Availability

Pharmacies, supermarkets

Approval Status

Approved by health authorities

Patent Status

Off-patent

WHO Essential Medicine

Yes

Clinical Trials

Extensive clinical history for antacids; specific trials for Gcool would depend on novel formulations.

Lab Monitoring

Serum electrolyte levels (magnesium, phosphate) for long-term high-dose use or in renal impairment.

Doctor Notes

Advise patients to shake well before use.
Emphasize timing separation from other medications.
Caution in patients with renal dysfunction.

Patient Guidelines

Shake well before each use.
Do not exceed the recommended dose.
Consult a doctor if symptoms persist for more than 2 weeks.
Avoid taking with other medications simultaneously.

Missed Dose Advice

If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and resume your regular dosing schedule. Do not double dose.