Gcool
Generic Name
Aluminum Hydroxide & Magnesium Hydroxide
Manufacturer
MediCare Pharma Ltd.
Country
Bangladesh
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Price Details
Current market pricing information
| Variant | Unit Price | Strip Price |
|---|---|---|
| gcool 500 mg suspension | ৳ 300.00 | N/A |
Description
Overview of the medicine
Gcool 500 mg Suspension is an antacid preparation used to relieve symptoms of heartburn, indigestion, and acid reflux. It contains active ingredients that neutralize stomach acid.
Uses & Indications
Dosage
Adults
10-20 ml (equivalent to 1-2 measuring spoonfuls) four times daily, between meals and at bedtime, or as directed by physician.
Elderly
No specific dose adjustment needed, but caution in renal impairment.
Renal_impairment
Use with caution. Higher risk of hypermagnesemia or aluminum toxicity. Consult a physician.
How to Take
Shake well before use. Take orally, preferably between meals and at bedtime. Do not take within 1-2 hours of other medications.
Mechanism of Action
Antacids work by neutralizing hydrochloric acid in the stomach, thereby increasing the pH of gastric contents. Aluminum hydroxide and magnesium hydroxide act locally in the stomach.
Pharmacokinetics
Onset
Within 5-15 minutes
Excretion
Mainly fecal excretion of unreacted drug; absorbed ions are renally excreted.
Half life
Not applicable for local action; absorbed ions are renally excreted within hours.
Absorption
Minimal systemic absorption of aluminum and magnesium ions, though some magnesium may be absorbed, especially in renal impairment. Local action in the gastrointestinal tract.
Metabolism
Not significantly metabolized; primary action is neutralization.
Side Effects
Contraindications
- •Hypersensitivity to any component
- •Severe renal impairment
- •Hypophosphatemia
Drug Interactions
Digoxin
Decreased absorption of digoxin. Separate administration.
Iron supplements
Decreased absorption of iron. Separate administration.
Tetracyclines & Fluoroquinolones
Decreased absorption due to chelation. Separate administration by at least 2-4 hours.
Storage
Store below 30°C in a dry place, away from light. Do not freeze. Keep out of reach of children.
Overdose
Symptoms may include diarrhea, constipation, nausea, vomiting, abdominal pain. In severe cases with renal impairment, hypermagnesemia (muscle weakness, hypotension, respiratory depression) or aluminum toxicity (osteomalacia, encephalopathy) may occur. Treatment is symptomatic and supportive.
Pregnancy & Lactation
Generally considered safe for use during pregnancy and lactation, but use with caution and consult a doctor. Avoid prolonged use of high doses.
Frequently Asked Questions
Common questions about this medicine
Pack Sizes
Shelf Life
24 months from manufacturing date
Availability
Pharmacies, supermarkets
Approval Status
Approved by health authorities
Patent Status
Off-patent
WHO Essential Medicine
YesAlternative Medicines in Bangladesh
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Global Brand Names
International brand names for this medicine
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