gentosep
Generic Name
Gentamicin 0.3% Cream
Manufacturer
Incepta Pharmaceuticals Ltd.
Country
Bangladesh
Loading images...
Price Details
Current market pricing information
| Variant | Unit Price | Strip Price |
|---|---|---|
| gentosep 03 cream | ৳ 18.50 | N/A |
Description
Overview of the medicine
Gentosep-03 Cream contains Gentamicin, an aminoglycoside antibiotic, used to treat various bacterial skin infections. It works by stopping the growth of bacteria.
Uses & Indications
Dosage
Adults
Apply a thin layer to the affected skin area 2-3 times daily. Gently rub in.
Elderly
No specific dose adjustment required.
Renal_impairment
No specific dose adjustment required for topical application.
How to Take
For external use only. Wash hands before and after applying the cream. Cleanse the affected area before application. Do not apply to eyes, mouth, or other mucous membranes.
Mechanism of Action
Gentamicin inhibits bacterial protein synthesis by binding to the 30S ribosomal subunit, leading to misreading of the mRNA code and premature termination of protein synthesis, ultimately causing bacterial cell death.
Pharmacokinetics
Onset
Clinical improvement usually observed within a few days.
Excretion
Primarily excreted unchanged via urine if significant systemic absorption occurs, but usually negligible after topical use.
Half life
Not well-defined for topical application due to minimal absorption.
Absorption
Minimal systemic absorption through intact skin. Absorption may increase with damaged skin or occlusive dressings.
Metabolism
Not extensively metabolized systemically after topical application.
Side Effects
Contraindications
- Hypersensitivity to Gentamicin or any component of the cream
- Viral or fungal skin infections (untreated)
- Tuberculosis of the skin
Drug Interactions
Other topical preparations
Avoid concurrent use of other topical preparations on the same area unless directed by a doctor to prevent potential interactions or reduced efficacy.
Storage
Store below 30°C in a dry place, away from light. Keep out of reach of children.
Overdose
Topical overdose is unlikely to cause systemic effects due to minimal absorption. Excessive application may increase local side effects. In case of accidental ingestion, seek medical attention.
Pregnancy & Lactation
Use with caution during pregnancy and lactation only if clearly needed and advised by a doctor. Minimal systemic absorption is expected.
Side Effects
Contraindications
- Hypersensitivity to Gentamicin or any component of the cream
- Viral or fungal skin infections (untreated)
- Tuberculosis of the skin
Drug Interactions
Other topical preparations
Avoid concurrent use of other topical preparations on the same area unless directed by a doctor to prevent potential interactions or reduced efficacy.
Storage
Store below 30°C in a dry place, away from light. Keep out of reach of children.
Overdose
Topical overdose is unlikely to cause systemic effects due to minimal absorption. Excessive application may increase local side effects. In case of accidental ingestion, seek medical attention.
Pregnancy & Lactation
Use with caution during pregnancy and lactation only if clearly needed and advised by a doctor. Minimal systemic absorption is expected.
Frequently Asked Questions
Common questions about this medicine
Pack Sizes
Shelf Life
24 months
Availability
Pharmacies nationwide
Approval Status
Approved by DGDA
Patent Status
Off-patent
Clinical Trials
Information on specific clinical trials for this exact formulation may vary, but gentamicin's efficacy in topical infections is well-established through numerous studies.
Lab Monitoring
- Generally not required for topical use.
Doctor Notes
- Advise patients on proper application technique and hygiene.
- Monitor for signs of superinfection or allergic reactions, especially with prolonged use.
- Emphasize completion of the full course to prevent resistance.
Patient Guidelines
- Complete the full course of treatment even if symptoms improve.
- Avoid contact with eyes and mucous membranes.
- Do not cover the treated area with occlusive dressings unless advised by a doctor.
- Discontinue use and consult a doctor if irritation or allergic reaction occurs.
Missed Dose Advice
If you miss a dose, apply it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not apply extra cream to make up for a missed dose.
Driving Precautions
Gentosep-03 Cream is not expected to affect the ability to drive or operate machinery.
Lifestyle Advice
- Maintain good hygiene of the affected area.
- Avoid sharing towels or personal items to prevent spread of infection.
Alternative Medicines in Bangladesh
Similar medicines available in the market
Global Brand Names
International brand names for this medicine. Click a brand to search for detailed information.