Goodgut
Generic Name
Saccharomyces boulardii
Manufacturer
Goodgut Pharma Inc.
Country
Bangladesh
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Description
Overview of the medicine
Goodgut is a probiotic supplement containing Saccharomyces boulardii, a beneficial yeast used to restore natural gut flora, support digestive health, and manage various types of diarrhea.
Uses & Indications
Dosage
Adults
1-2 capsules daily, or as directed by a physician.
Elderly
Same as adult dosage.
Renal_impairment
No specific dosage adjustment required.
How to Take
Capsules can be swallowed whole with water. For children or those with difficulty swallowing, capsules can be opened and the contents mixed with food or a beverage (not hot).
Mechanism of Action
Saccharomyces boulardii works by maintaining and restoring the normal balance of gut microbiota. It helps to inhibit the growth of pathogenic bacteria, reduce inflammation, and improve gut barrier function.
Pharmacokinetics
Onset
Effect can be seen within 1-2 days for acute diarrhea.
Excretion
Excreted unchanged in feces within a few days after cessation of treatment.
Half life
Not applicable as it's a living organism that passes through the gut.
Absorption
Not absorbed systemically; acts locally in the gut.
Metabolism
Not metabolized by the human body; maintains metabolic activity within the gut.
Side Effects
Contraindications
- Patients with central venous catheter (risk of fungemia)
- Immunocompromised patients
- Known hypersensitivity to yeast
Drug Interactions
Antifungal agents
Antifungal agents (e.g., fluconazole, nystatin) may reduce the efficacy of Saccharomyces boulardii. Administer at a different time of day.
Storage
Store below 25°C in a dry place, protected from light and moisture. Keep out of reach of children.
Overdose
No specific overdose symptoms are known. In case of excessive intake, consult a healthcare professional.
Pregnancy & Lactation
Generally considered safe, but consult a healthcare professional before use during pregnancy or lactation.
Side Effects
Contraindications
- Patients with central venous catheter (risk of fungemia)
- Immunocompromised patients
- Known hypersensitivity to yeast
Drug Interactions
Antifungal agents
Antifungal agents (e.g., fluconazole, nystatin) may reduce the efficacy of Saccharomyces boulardii. Administer at a different time of day.
Storage
Store below 25°C in a dry place, protected from light and moisture. Keep out of reach of children.
Overdose
No specific overdose symptoms are known. In case of excessive intake, consult a healthcare professional.
Pregnancy & Lactation
Generally considered safe, but consult a healthcare professional before use during pregnancy or lactation.
Frequently Asked Questions
Common questions about this medicine
Pack Sizes
Shelf Life
24 months
Availability
Pharmacies, Supermarkets, Online
Approval Status
Approved by regulatory authorities
Patent Status
Patent expired for generic
Clinical Trials
Numerous clinical trials have demonstrated the efficacy of Saccharomyces boulardii in preventing and treating various forms of diarrhea and improving gut health.
Lab Monitoring
- Generally not required for routine use.
Doctor Notes
- Advise patients on proper storage and administration.
- Caution in immunocompromised patients or those with CVC due to fungemia risk.
- Can be used as an adjunct in antibiotic therapy.
Patient Guidelines
- Take as directed, do not exceed recommended dose.
- Store in a cool, dry place away from direct sunlight.
- Inform your doctor if you are immunocompromised or have a central venous catheter.
Missed Dose Advice
If a dose is missed, take it as soon as you remember. If it is almost time for the next dose, skip the missed dose and resume your regular dosing schedule. Do not double the dose.
Driving Precautions
Goodgut is not known to impair the ability to drive or operate machinery.
Lifestyle Advice
- Maintain a healthy diet rich in fiber.
- Drink plenty of fluids.
- Avoid excessive intake of processed foods.
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International brand names for this medicine. Click a brand to search for detailed information.
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